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Parvifolixanthone A

CAS# 906794-56-7

Parvifolixanthone A

Catalog No. BCN7354----Order now to get a substantial discount!

Product Name & Size Price Stock
Parvifolixanthone A: 5mg $960 In Stock
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Quality Control of Parvifolixanthone A

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Chemical structure

Parvifolixanthone A

3D structure

Chemical Properties of Parvifolixanthone A

Cas No. 906794-56-7 SDF Download SDF
PubChem ID 16085273 Appearance Powder
Formula C28H32O6 M.Wt 464.55
Type of Compound Xanthones Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 1,3,5,6-tetrahydroxy-2,4,7-tris(3-methylbut-2-enyl)xanthen-9-one
SMILES CC(=CCC1=C(C(=C2C(=C1)C(=O)C3=C(O2)C(=C(C(=C3O)CC=C(C)C)O)CC=C(C)C)O)O)C
Standard InChIKey UVAAZIOBAWMBHC-UHFFFAOYSA-N
Standard InChI InChI=1S/C28H32O6/c1-14(2)7-10-17-13-20-25(32)21-24(31)18(11-8-15(3)4)23(30)19(12-9-16(5)6)27(21)34-28(20)26(33)22(17)29/h7-9,13,29-31,33H,10-12H2,1-6H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Parvifolixanthone A

The twigs of Garcinia parvifolia.

Biological Activity of Parvifolixanthone A

DescriptionParvifolixanthone A is a natural product from Garcinia parvifolia.
In vitro

Chemical constituents from stem barks of Garcinia paucinervis.[Reference: WebLink]

Chinese Traditional & Herbal Drugs, 2012, 43(3):436-439.

To study the chemical constituents from the stem barks of Garcinia paucinervis and their antitumor activities.
METHODS AND RESULTS:
Chemical constituents were isolated and purified from petroleum ether extract of G.paucinervis by chromatography on silica gel,RP-18,Sephadex LH-20 column,and preparative TLC.Their structures were identified on the basis of spectroscopic analysis and chemical evidence.The antitumor activity was screened by MTT assay. Ten compounds were isolated and identified as cambogin(1),pyromeconic acid(2),β-sitosterol(3),daucosterol(4),7-prenyljacareubin(5),Parvifolixanthone A(6),formoxanthone A(7),termicalcicolanone A(8),1,3,5,6-tetrahydroxy-4-prenylxanthone(9),and isogarcinol(10).Compounds 5 and 7 showed moderate cytotoxic activity against HL-60,SMMC-7721,A549,MCF-7,and SW480 cell lines.
CONCLUSIONS:
Compounds 2—5 and 7—10 are isolated from this plant for the first time and the13C-NMR spectroscopic data of compound 5 are firstly reported.

Protocol of Parvifolixanthone A

Structure Identification
Tetrahedron, 2006, 62(36):8578-8585.

Phloroglucinols, depsidones and xanthones from the twigs of Garcinia parvifolia.[Reference: WebLink]


METHODS AND RESULTS:
Seven phloroglucinols, named parvifoliols A–G (1–7), two depsidones, named parvifolidones A, B (8, 9), and three xanthones, named Parvifolixanthone A, parvifolixanthone B, parvifolixanthone C (10–12), were isolated from the twigs of Garcinia parvifolia along with seven known compounds: garcidepsidone B, mangostinone, rubraxanthone, dulxanthone D, 1,3,5,6-tetrahydroxyxanthone, norathyriol, and (2E,6E,10E)-( )-4β-hydroxy-3-methyl-5β-(3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraenyl)cyclohex-2-en-1-one.
CONCLUSIONS:
Their structures were proposed on the basis of spectroscopic data. The antibacterial and antioxidation activities were evaluated.

Parvifolixanthone A Dilution Calculator

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Preparing Stock Solutions of Parvifolixanthone A

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.1526 mL 10.7631 mL 21.5262 mL 43.0524 mL 53.8155 mL
5 mM 0.4305 mL 2.1526 mL 4.3052 mL 8.6105 mL 10.7631 mL
10 mM 0.2153 mL 1.0763 mL 2.1526 mL 4.3052 mL 5.3816 mL
50 mM 0.0431 mL 0.2153 mL 0.4305 mL 0.861 mL 1.0763 mL
100 mM 0.0215 mL 0.1076 mL 0.2153 mL 0.4305 mL 0.5382 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Parvifolixanthone A

Chemical constituents from stem barks of Garcinia paucinervis.

Chinese Traditional & Herbal Drugs, 2012, 43(3):436-439.

To study the chemical constituents from the stem barks of Garcinia paucinervis and their antitumor activities.Methods Chemical constituents were isolated and purified from petroleum ether extract of G.paucinervis by chromatography on silica gel,RP-18,Sephadex LH-20 column,and preparative TLC.Their structures were identified on the basis of spectroscopic analysis and chemical evidence.The antitumor activity was screened by MTT assay.Results Ten compounds were isolated and identified as cambogin(1),pyromeconic acid(2),β-sitosterol(3),daucosterol(4),7-prenyljacareubin(5),Parvifolixanthone A(6),formoxanthone A(7),termicalcicolanone A(8),1,3,5,6-tetrahydroxy-4-prenylxanthone(9),and isogarcinol(10).Compounds 5 and 7 showed moderate cytotoxic activity against HL-60,SMMC-7721,A549,MCF-7,and SW480 cell lines.Conclusion Compounds 2—5 and 7—10 are isolated from this plant for the first time and the13C-NMR spectroscopic data of compound 5 are firstly reported.

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