Pelargonidin-3-O-glucoside chlorideCAS# 18466-51-8 |
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| Cas No. | 18466-51-8 | SDF | Download SDF |
| PubChem ID | 3080714 | Appearance | Dark, reddish powder |
| Formula | C21H21O10Cl | M.Wt | 468.8 |
| Type of Compound | Flavonoids | Storage | Desiccate at -20°C |
| Synonyms | Callistephin chloride | ||
| Solubility | Soluble in methan | ||
| Chemical Name | (2S,3R,4S,5S,6R)-2-[5,7-dihydroxy-2-(4-hydroxyphenyl)chromenylium-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol;chloride | ||
| SMILES | C1=CC(=CC=C1C2=C(C=C3C(=CC(=CC3=[O+]2)O)O)OC4C(C(C(C(O4)CO)O)O)O)O.[Cl-] | ||
| Standard InChIKey | CAHGSEFWVUVGGL-UBNZBFALSA-N | ||
| Standard InChI | InChI=1S/C21H20O10.ClH/c22-8-16-17(26)18(27)19(28)21(31-16)30-15-7-12-13(25)5-11(24)6-14(12)29-20(15)9-1-3-10(23)4-2-9;/h1-7,16-19,21-22,26-28H,8H2,(H2-,23,24,25);1H/t16-,17-,18+,19-,21-;/m1./s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1. Pelargonidin-3-O-glucopyranoside has antioxidant and anti-inflammatory activities. 2. Pelargonidin-3-O-glucopyranoside is the glucoside of Pelargonidin, an potential antidiabetic agent. 2. Pelargonidin-3-O-glucopyranoside exerts potential anti-estrogenic, and angiotensin-converting enzyme inhibitory activities. |
| Targets | Estrogen receptor | Immunology & Inflammation related | Progestogen receptor |
Pelargonidin-3-O-glucoside chloride Dilution Calculator
Pelargonidin-3-O-glucoside chloride Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.1331 mL | 10.6655 mL | 21.3311 mL | 42.6621 mL | 53.3276 mL |
| 5 mM | 0.4266 mL | 2.1331 mL | 4.2662 mL | 8.5324 mL | 10.6655 mL |
| 10 mM | 0.2133 mL | 1.0666 mL | 2.1331 mL | 4.2662 mL | 5.3328 mL |
| 50 mM | 0.0427 mL | 0.2133 mL | 0.4266 mL | 0.8532 mL | 1.0666 mL |
| 100 mM | 0.0213 mL | 0.1067 mL | 0.2133 mL | 0.4266 mL | 0.5333 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Interaction of selected anthocyanins with erythrocytes and liposome membranes.[Pubmed:22396139]
Cell Mol Biol Lett. 2012 Jun;17(2):289-308.
Anthocyanins are one of the main flavonoid groups. They are responsible for, e.g., the color of plants and have antioxidant features and a wide spectrum of medical activity. The subject of the study was the following compounds that belong to the anthocyanins and which can be found, e.g., in strawberries and chokeberries: callistephin chloride (Pelargonidin-3-O-glucoside chloride) and ideain chloride (cyanidin-3-O-galactoside chloride). The aim of the study was to determine the compounds' antioxidant activity towards the erythrocyte membrane and changes incurred by the tested anthocyanins in the lipid phase of the erythrocyte membrane, in liposomes composed of erythrocyte lipids and in DPPC, DPPC/cholesterol and egg lecithin liposomes. In particular, we studied the effect of the two selected anthocyanins on red blood cell morphology, on packing order in the lipid hydrophilic phase, on fluidity of the hydrophobic phase, as well as on the temperature of phase transition in DPPC and DPPC/cholesterol liposomes. Fluorimetry with the Laurdan and Prodan probes indicated increased packing density in the hydrophilic phase of the membrane in the presence of anthocyanins. Using the fluorescence probes DPH and TMA-DPH, no effect was noted inside the hydrophobic phase of the membrane, as the lipid bilayer fluidity was not modified. The compounds slightly lowered the phase transition temperature of phosphatidylcholine liposomes. The study has shown that both anthocyanins are incorporated into the outer region of the erythrocyte membrane, affecting its shape and lipid packing order, which is reflected in the increasing number of echinocytes. The investigation proved that the compounds penetrate only the outer part of the external lipid layer of liposomes composed of erythrocyte lipids, DPPC, DPPC/cholesterol and egg lecithin lipids, changing its packing order. Fluorimetry studies with DPH-PA proved that the tested anthocyanins are very effective antioxidants. The antioxidant activity of the compounds was comparable with the activity of Trolox(R).
