Plumbagic acidCAS# 75640-06-1 |
Quality Control & MSDS
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Number of papers citing our products
| Cas No. | 75640-06-1 | SDF | Download SDF |
| PubChem ID | N/A | Appearance | Powder |
| Formula | C11H12O5 | M.Wt | 224.2 |
| Type of Compound | Phenols | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
Plumbagic acid Dilution Calculator
Plumbagic acid Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 4.4603 mL | 22.3015 mL | 44.603 mL | 89.2061 mL | 111.5076 mL |
| 5 mM | 0.8921 mL | 4.4603 mL | 8.9206 mL | 17.8412 mL | 22.3015 mL |
| 10 mM | 0.446 mL | 2.2302 mL | 4.4603 mL | 8.9206 mL | 11.1508 mL |
| 50 mM | 0.0892 mL | 0.446 mL | 0.8921 mL | 1.7841 mL | 2.2302 mL |
| 100 mM | 0.0446 mL | 0.223 mL | 0.446 mL | 0.8921 mL | 1.1151 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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[Chemical Constituents of the Aerial Parts from Plumbago zeylanica].[Pubmed:30203952]
Zhong Yao Cai. 2016 Jul;39(7):1541-4.
OBJECTIVE: To study the anti-oxidative constituents of the aerial parts of Plumbago zeylanica. METHODS: The ethanol extract of Plumbago zeylanica was separated and purified by various chromatographic techniques. On the basis of various spectroscopic data, the structures of isolated compounds were elucidated. ABTS+radical scavenging were carried out in antioxidant activity evaluation of the isolated compounds. RESULTS: Eleven compounds were isolated and identified as cis-isoshinanolone-4-O-beta-D-glucopyranoside( 1),tachioside( 2),2,6-dimethoxy-p-hydroquinone-1-O-beta-D-glucopyranoside( 3),3-( beta-D-glucopyranosyloxy)-4-methoxybenzoic acid( 4),3'-O-beta-D-glucopyranosyloxy-Plumbagic acid( 5),3'-O-beta-D-glucopyranosyloxy-Plumbagic acid methyl ester( 6),Plumbagic acid( 7),plumbagine A( 8),plumbagine C( 9),syringate-4-O-beta-D-glucopyranoside( 10) and 2-methyl-5-hydroxychromone( 11). Compounds 2,3,and5 displayed significant scavenging effect on ABTS+. CONCLUSION: Compounds 1 ~ 4,10,11 are obtained from this plant for the first time. Compounds 2,3,and 5 show significant anti-oxidative effects.
[Chemical constituents from aerial parts of Plumbago zeylanica Linn].[Pubmed:17727061]
Zhong Yao Cai. 2007 May;30(5):558-60.
OBJECTIVE: To investigate the chemical constituents of the aerial parts of Plumbago zeylanica Linn. METHODS: The constituents of the EtOAc-soluble portion in the 95% ethanol extract were isolated and purified by means of chromatography. Compounds were identified by their physical characteristics and spectral features. RESULTS: Nine compounds were isolated as plumbagin (I), isoshinanolone (II), Plumbagic acid (III), beta-sitosterol (IV), 4-hydroxybenzaldehyde (V), trans-cinnamic acid (VI), vanillic acid (VII), 2, 5-dimethyl-7-hydroxychromone (VIII), indole-3-carboxaldehyde (IX). CONCLUSION: Compounds V, VII, VIII and IX were isolated for the first time from Plumbago Linn.
Cytotoxic naphthoquinones and plumbagic acid glucosides from Plumbago zeylanica.[Pubmed:12560036]
Phytochemistry. 2003 Feb;62(4):619-22.
Two Plumbagic acid glucosides, 3'-O-beta-glucopyranosyl Plumbagic acid and 3'-O-beta-glucopyranosyl Plumbagic acid methylester along with five naphthoquinones (plumbagin, chitranone, maritinone, elliptinone and isoshinanolone), and five coumarins (seselin, 5-methoxyseselin, suberosin, xanthyletin and xanthoxyletin) were isolated from the roots of Plumbago zeylanica. All coumarins were not previously found in this plant. Cytotoxicity of these compounds to various tumor cells lines was evaluated, and plumbagin significantly suppressed growth of Raji, Calu-1, HeLa, and Wish tumor cell lines.
