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Cryptostigmin II

CAS# 50906-57-5

Cryptostigmin II

2D Structure

Catalog No. BCX2136----Order now to get a substantial discount!

Product Name & Size Price Stock
Cryptostigmin II: 5mg $200 In Stock
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Quality Control of Cryptostigmin II

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Cryptostigmin II

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Chemical Properties of Cryptostigmin II

Cas No. 50906-57-5 SDF Download SDF
PubChem ID N/A Appearance Powder
Formula C37H56O15 M.Wt 740.8
Type of Compound Steroids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Cryptostigmin II

The herbs of Nerium oleander L.

Cryptostigmin II Dilution Calculator

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Cryptostigmin II Molarity Calculator

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Preparing Stock Solutions of Cryptostigmin II

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.3499 mL 6.7495 mL 13.4989 mL 26.9978 mL 33.7473 mL
5 mM 0.27 mL 1.3499 mL 2.6998 mL 5.3996 mL 6.7495 mL
10 mM 0.135 mL 0.6749 mL 1.3499 mL 2.6998 mL 3.3747 mL
50 mM 0.027 mL 0.135 mL 0.27 mL 0.54 mL 0.6749 mL
100 mM 0.0135 mL 0.0675 mL 0.135 mL 0.27 mL 0.3375 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Cryptostigmin II

Two New Cyototoxic Cardenolides from the Whole Plants of Adonis multiflora Nishikawa & Koki Ito.[Pubmed:26610451]

Molecules. 2015 Nov 23;20(11):20823-31.

A phytochemical investigation of the whole plants of Adonis multiflora Nishikawa & Koki Ito. resulted in the isolation and identification of two new cardenolides--adonioside A (1) and adonioside B (6)--as well as four known cardenolides: tupichinolide (2) oleandrine (3), Cryptostigmin II (4), and cymarin (5). Their structures were elucidated on the basis of NMR, MS, and IR spectroscopic analyses. Compounds 1, 2, 5, and 6 showed significant cytotoxicity against six human cancer cell lines (HCT-116, HepG2, HeLa, SK-OV-3, and SK-MEL-5, and SK-BR-3).

Cardiac glycosides from shoot cultures of Cryptostegia grandiflora.[Pubmed:21808532]

Pharmacognosy Res. 2010 Jan;2(1):15-8.

Cardiac glycosides in shoot cultures of Cryptostegia grandiflora were identified when grown in modified MS medium. The change in shoot segments and cardiac glycosides content was followed between day zero and day 12 at 2-day intervals. The content of cardiac glycosides in leaves and shoot cultures of Cryptostegia grandiflora was monitored by HPLC. Two major compounds were detected and isolated from shoot cultures extract, named oleandrigenin 3-O-beta - glucopyranosyl-(1-->4) - beta-cymaropyranosyl-(1-->4)-beta-digitoxopyranoside (cryptostigmin I) and oleandrigenin 3-O-beta - glucopyranosyl-(1-->4)-alpha-rhamnopyranoside (Cryptostigmin II). The structures of the isolated compounds were verified by means of MS and NMR spectral analysis, as well as by comparison with authentic samples. The leaves and shoot cultures were analyzed for their cardiac glycosides content. The shoot cultures inoculated into MS-based culture media supplemented with 0.1 mg L(-1) BA, 30 g L(-1) sucrose, 0.1 g L(-1)myo-inositol and 0.1 g L(-1) ascorbic acid were found to contain a quantity of cardiac glycosides that was about four fold the cardiac glycosides content of leaves extract.

Cardiac glycosides from Cryptostegia grandiflora.[Pubmed:11576593]

Phytochemistry. 2001 Oct;58(4):537-42.

From the leaves of Cryptostegia grandiflora, four new cardiac glycosides oleandrigenin 3-O-beta-glucopyranosyl-(1-->4)-beta-cymaropyranosyl-(1-->4)-beta-digitoxopyranoside, cryptostigmin I, oleandrigenin 3-O-beta-glucopyranosyl-(1-->4)-alpha-rhamnopyranoside, Cryptostigmin II, 16-propionylgitoxigenin 3-O-beta-glucopyranosyl-(1-->4)-alpha-rhamnopyranoside, Cryptostigmin III and oleandrigenin 3-O-beta-glucopyranosyl-(1-->6)-beta-glucopyranosyl-(1-->4)-beta-cymaropyranosyl-(1-->4)-beta-digitoxopyranoside, cryptostigmin IV have been isolated together with two known cardenolides subalpinosid and 16-O-acetyl-digitalinum verum. The structures of the isolated compounds were verified by means of MS and NMR spectral analyses.

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