Pyrolin

CAS# 95-71-6

Pyrolin

Catalog No. BCN6902----Order now to get a substantial discount!

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Pyrolin: 5mg Please Inquire In Stock
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Quality Control of Pyrolin

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Chemical structure

Pyrolin

3D structure

Chemical Properties of Pyrolin

Cas No. 95-71-6 SDF Download SDF
PubChem ID 7253 Appearance Powder
Formula C7H8O2 M.Wt 124.14
Type of Compound Phenols Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 2-methylbenzene-1,4-diol
SMILES CC1=C(C=CC(=C1)O)O
Standard InChIKey CNHDIAIOKMXOLK-UHFFFAOYSA-N
Standard InChI InChI=1S/C7H8O2/c1-5-4-6(8)2-3-7(5)9/h2-4,8-9H,1H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Pyrolin

The herbs of Pyrola calliantha H. Andr.

Biological Activity of Pyrolin

Description1. Pyrolin has a strong antifungal activity and exerts a potent impact on the ultrastructure of M.fructicola.
TargetsAntifection

Pyrolin Dilution Calculator

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Pyrolin Molarity Calculator

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Preparing Stock Solutions of Pyrolin

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 8.0554 mL 40.2771 mL 80.5542 mL 161.1084 mL 201.3855 mL
5 mM 1.6111 mL 8.0554 mL 16.1108 mL 32.2217 mL 40.2771 mL
10 mM 0.8055 mL 4.0277 mL 8.0554 mL 16.1108 mL 20.1386 mL
50 mM 0.1611 mL 0.8055 mL 1.6111 mL 3.2222 mL 4.0277 mL
100 mM 0.0806 mL 0.4028 mL 0.8055 mL 1.6111 mL 2.0139 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Pyrolin

Inhibitory Effect and Antimicrobial Mechanism of Pyrolin on Monilinia fructicola in Peach

Scientia Agricultura Sinica, 2009,42 (8) :2784-2792.

To explore the antifungal activity and potential mechanism of Pyrolin against Monilinia fructicola.【Method】 Agar plate tests was conducted to test the inhibitory effect in-vitro and in vivo of Pyrolin.And doubling dilution method was used to determine the minimal inhibitory concentration(MIC) and minimal fugicide concentration(MFC).Polyphenol oxidase(PPO),peroxidase(POD) and phenylalanine ammonium-lyase(PAL) activities induced by inoculation with Pyrolin and M.fructicola were studied in peach.The ultrastructure of M.fructicola treated by Pyrolin was observed through scanning electron microscope(SEM) and transmission electron microscope(TEM).【Result】 Pyrolin displayed strong antifungal activity to M.fructicola and the activity was significantly increased when the applied concentration was higher,the MIC value of 0.032 mg·mL-1 and MFC value of 0.156 mg·mL-1.The activities of PPO,POD and PAL in peach increased significantly when inoculated with Pyrolin and M.fructicola,and maintained at a high level throughout the experiment.The observations with SEM revealed that the hyphae distorted,the adhesions mycelium occurred,the cell wall was rupture,cell surface occurred substance of flocculent agglutination.The observations with TEM showed that the hypha became thinning obviously,the inner structure confused,the hyphal cell was damaged severely.【Conclusion】 Pyrolin has a strong antifungal activity and exerts a potent impact on the ultrastructure of M.fructicola.

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