Home >> Research Area >>Others>>Others>> Sodium formononetin-3'-sulfonate

Sodium formononetin-3'-sulfonate

Used for myocardial preservation CAS# 949021-68-5

Sodium formononetin-3'-sulfonate

Catalog No. BCC1960----Order now to get a substantial discount!

Product Name & Size Price Stock
Sodium formononetin-3'-sulfonate: 5mg $288 In Stock
Sodium formononetin-3'-sulfonate: 10mg Please Inquire In Stock
Sodium formononetin-3'-sulfonate: 20mg Please Inquire Please Inquire
Sodium formononetin-3'-sulfonate: 50mg Please Inquire Please Inquire
Sodium formononetin-3'-sulfonate: 100mg Please Inquire Please Inquire
Sodium formononetin-3'-sulfonate: 200mg Please Inquire Please Inquire
Sodium formononetin-3'-sulfonate: 500mg Please Inquire Please Inquire
Sodium formononetin-3'-sulfonate: 1000mg Please Inquire Please Inquire
Related Products

Quality Control of Sodium formononetin-3'-sulfonate

Number of papers citing our products

Chemical structure

Sodium formononetin-3'-sulfonate

3D structure

Chemical Properties of Sodium formononetin-3'-sulfonate

Cas No. 949021-68-5 SDF Download SDF
PubChem ID 51037709 Appearance Powder
Formula C16H13NaO7S M.Wt 372.33
Type of Compound N/A Storage Desiccate at -20°C
Synonyms Sul-F
Solubility H2O : 25 mg/mL (67.51 mM; Need ultrasonic)
Chemical Name sodium;5-(7-hydroxy-4-oxochromen-3-yl)-2-methoxybenzenesulfonate
SMILES COC1=C(C=C(C=C1)C2=COC3=C(C2=O)C=CC(=C3)O)S(=O)(=O)[O-].[Na+]
Standard InChIKey MEFDNOYSDRFHOA-UHFFFAOYSA-M
Standard InChI InChI=1S/C16H12O7S.Na/c1-22-13-5-2-9(6-15(13)24(19,20)21)12-8-23-14-7-10(17)3-4-11(14)16(12)18;/h2-8,17H,1H3,(H,19,20,21);/q;+1/p-1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Biological Activity of Sodium formononetin-3'-sulfonate

DescriptionSodium formononetin-3'-sulfonate (Sul-F) is a water-sol. derivate of formononetin. IC50 value: Target: Research results showed that treatment with Sul-F significantly prevented the elevation of ST-segment level, decreased the contents of creatine kinase-MB, lactate dehydrogenase, alanine aminotransferase and cardiac troponin T in serum and reduced the myocardium necrosis scores. These findings indicate that Sul-F has a protective potential against myocardial infarction injury. A possible mechanism for the protective effect is the elevated expression of endogenous antioxidant defense enzymes degraded lipid peroxidn. products and improved energy metab. of cardiac mitochondrial, thus attenuating cardiocyte apoptosis. Other reaearch results showed that sodium formononetin-3'-sulfonate not only had favorable water, solubility but also had good lipid-lowering and liver-protection activities.

References:
[1]. Zhang, Shumin; Tang, Xuexi; Tian, Jingwei et al. Cardioprotective effect of sulphonated formononetin on acute myocardial infarction in rats. Basic & Clinical Pharmacology & Toxicology (2011), 108(6), 390-395. [2]. Wang, Qiuya; Meng, Qinghua; Zhang, Zunting et al. Synthesis, solubility, lipids-lowering and liver-protection activities of sulfonated formononetin. Yaoxue Xuebao (2009), 44(4), 386-389. [3]. Cardioprotective Effect of Sulfonated Formononetin on Acute Myocardial Infarction in Rats.

Sodium formononetin-3'-sulfonate Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

Sodium formononetin-3'-sulfonate Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of Sodium formononetin-3'-sulfonate

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.6858 mL 13.4289 mL 26.8579 mL 53.7158 mL 67.1447 mL
5 mM 0.5372 mL 2.6858 mL 5.3716 mL 10.7432 mL 13.4289 mL
10 mM 0.2686 mL 1.3429 mL 2.6858 mL 5.3716 mL 6.7145 mL
50 mM 0.0537 mL 0.2686 mL 0.5372 mL 1.0743 mL 1.3429 mL
100 mM 0.0269 mL 0.1343 mL 0.2686 mL 0.5372 mL 0.6714 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University

Background on Sodium formononetin-3'-sulfonate

Sodium formononetin-3'-sulfonate (Sul-F) is a water-sol. derivate of formononetin. Research results showed that treatment with Sul-F significantly prevented the elevation of ST-segment level, decreased the contents of creatine kinase-MB, lactate dehydrogenase, alanine aminotransferase and cardiac troponin T in serum and reduced the myocardium necrosis scores. These findings indicate that Sul-F has a protective potential against myocardial infarction injury. A possible mechanism for the protective effect is the elevated expression of endogenous antioxidant defense enzymes degraded lipid peroxidn. products and improved energy metab. of cardiac mitochondrial, thus attenuating cardiocyte apoptosis. Other reaearch results showed that sodium formononetin-3'-sulfonate not only had favorable water, solubility but also had good lipid-lowering and liver-protection activities.

Featured Products
New Products
 

References on Sodium formononetin-3'-sulfonate

Spray-Dried Sodium Zirconate: A Rapid Absorption Powder for CO2 Capture with Enhanced Cyclic Stability.[Pubmed:28371521]

ChemSusChem. 2017 May 9;10(9):2059-2067.

Improved powders for capturing CO2 at high temperatures are required for H2 production using sorption-enhanced steam reforming. Here, we examine the relationship between particle structure and carbonation rate for two types of Na2 ZrO3 powders. Hollow spray-dried microgranules with a wall thickness of 100-300 nm corresponding to the dimensions of the primary acetate-derived particles gave about 75 wt % theoretical CO2 conversion after a process-relevant 5 min exposure to 15 vol % CO2 . A conventional powder prepared by solid-state reaction carbonated more slowly, achieving only 50 % conversion owing to a greater proportion of the reaction requiring bulk diffusion through the densely agglomerated particles. The hollow granular structure of the spray-dried powder was retained postcarbonation but chemical segregation resulted in islands of an amorphous Na-rich phase (Na2 CO3 ) within a crystalline ZrO2 particle matrix. Despite this phase separation, the reverse reaction to re-form Na2 ZrO3 could be achieved by heating each powder to 900 degrees C in N2 (no dwell time). This resulted in a very stable multicycle performance in 40 cycle tests using thermogravimetric analysis for both powders. Kinetic analysis of thermogravimetric data showed the carbonation process fits an Avrami-Erofeyev 2 D nucleation and nuclei growth model, consistent with microstructural evidence of a surface-driven transformation. Thus, we demonstrate that spray drying is a viable processing route to enhance the carbon capture performance of Na2 ZrO3 powder.

Comparison of the Efficacy of a Sulfuric Acid-Sodium Sulfate Blend and Lactic Acid for the Reduction of Salmonella on Prerigor Beef Carcass Surface Tissue.[Pubmed:28371589]

J Food Prot. 2017 Apr 3:809-813.

A study was conducted to compare the efficacy of a commercially available sulfuric acid-sodium sulfate blend (SSS) and lactic acid (LA) in reducing inoculated Salmonella populations on beef. Sixty pieces of prerigor beef carcass surface brisket tissue, collected directly from the processing line of a commercial beef processing plant, were cut into two sections (10 by 10 cm each) and spot inoculated (6 to 7 log CFU/cm(2)) on the adipose side with a six-strain mixture of Salmonella. One section per piece of brisket tissue was left untreated (control), while the second section was spray treated (5 s, 15 lb/in(2), and 33 mL/s flow rate) with unheated (21 degrees C) or heated (52 degrees C) solutions of SSS (pH 1.1) or LA (4%). Unheated and heated SSS lowered (P < 0.05) total bacterial counts from 6.3 to 4.6 and 4.3 log CFU/cm(2), respectively. Likewise, unheated and heated LA reduced (P < 0.05) total bacterial counts from 6.3 to 4.7 and 4.4 log CFU/cm(2), respectively. Initial counts of inoculated Salmonella populations (6.1 to 6.2 log CFU/cm(2)) were reduced (P < 0.05) to 4.2 and 3.9 log CFU/cm(2) following treatment with unheated and heated SSS, respectively, and to 3.7 and 3.8 log CFU/cm(2) after treatment with unheated and heated LA, respectively. Overall, the temperature of the chemical solutions had a small (0.3 log CFU/cm(2)), but significant (P < 0.05), effect on total bacterial counts but not (P > 0.05) on Salmonella counts. Regardless of solution temperature, Salmonella counts for LA-treated samples were 0.3 log CFU/cm(2) lower (P < 0.05) than those of samples treated with SSS. These results indicate that both unheated and heated solutions of SSS and LA are effective interventions for reducing Salmonella contamination on prerigor beef carcass surface tissue.

Reactivity enhancement of iron sulfide nanoparticles stabilized by sodium alginate: Taking Cr (VI) removal as an example.[Pubmed:28371713]

J Hazard Mater. 2017 Jul 5;333:275-284.

The widespread distribution of chromium(VI) in the environment leads to groundwater contamination. The use of iron sulfide (FeS) to remove Cr(VI) has therefore been proposed. However, aggregation is one of the main problems associated with the use of FeS nanoparticles prepared by traditional methods In this study, we used sodium alginate (SA) to stabilize FeS nanoparticles (FeS-SA). SA could prevent aggregation of FeS by the concurrent electrostatic repulsion and steric hindrance. Homogeneously dispersed FeS-SA nanoparticles 100nm in diameter were observed. FeS-SA showed high efficiency in Cr(VI) removal, corresponding to an enhancement of efficiency from 65% (7.50mmol Cr(VI) per g FeS) to 100% (11.54mmol Cr per g FeS) relative to that achieved with naked FeS. Analysis of reaction products by X-ray diffraction and X-ray photoelectron spectroscopy revealed the co-existence of alpha-FeOOH, S8, and Cr(OH)3 that apparently were introduced by Fe(II), S(-II), and Cr(VI), respectively. In-depth analysis of the removal mechanism revealed that reduction and adsorption respectively account for 82% and 18% of the Cr removal. In addition, higher pH and CaCl2 concentration resulted in lower removal efficiency. This study provides a promising application of SA in enhancing FeS reactivity for the remediation of groundwater pollution.

Porous CoFe2O4 nanocubes derived from metal-organic frameworks as high-performance anode for sodium ion batteries.[Pubmed:28371673]

J Colloid Interface Sci. 2017 Aug 1;499:145-150.

Recently sodium ion batteries (SIBs) as a new energy storage system have attracted enormous interests. Unfortunately, the development of high-performance electrode materials for SIBs is restricted owing to the large volume change during sodium insertion and extraction. In this work, porous CoFe2O4 nanocubes (PCFO-NCs) were prepared simply by annealing metal-organic frameworks and used as anode materials for SIBs. The PCFO-NCs exhibit a high initial Coulombic efficiency of 68.8% and a maximum reversible capacity of 360mAhg(-1) after 50 cycles at the current density of 50mAg(-1), as well as good rate capability and excellent cycling stability at high current density. The excellent electrochemical performance can be attributed the short diffusion distance of sodium ion due to the good interfacial contact between electrode and electrolyte, and the buffering of volume change during charge/discharge processes by the porous structure.

Description

Sodium formononetin-3'-sulfonate (Sul-F) is a water-sol.

Keywords:

Sodium formononetin-3'-sulfonate,949021-68-5,Sul-F,Natural Products,Others, buy Sodium formononetin-3'-sulfonate , Sodium formononetin-3'-sulfonate supplier , purchase Sodium formononetin-3'-sulfonate , Sodium formononetin-3'-sulfonate cost , Sodium formononetin-3'-sulfonate manufacturer , order Sodium formononetin-3'-sulfonate , high purity Sodium formononetin-3'-sulfonate

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: