H-Phe(4-NO2)-OH

CAS# 949-99-5

H-Phe(4-NO2)-OH

2D Structure

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H-Phe(4-NO2)-OH

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Chemical Properties of H-Phe(4-NO2)-OH

Cas No. 949-99-5 SDF Download SDF
PubChem ID 13706 Appearance Powder
Formula C9H10N2O4 M.Wt 210.2
Type of Compound N/A Storage Desiccate at -20°C
Synonyms 4-Nitro-L-phenylalanine
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES C1=CC(=CC=C1CC(C(=O)O)N)[N+](=O)[O-]
Standard InChIKey GTVVZTAFGPQSPC-QMMMGPOBSA-N
Standard InChI InChI=1S/C9H10N2O4/c10-8(9(12)13)5-6-1-3-7(4-2-6)11(14)15/h1-4,8H,5,10H2,(H,12,13)/t8-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

H-Phe(4-NO2)-OH Dilution Calculator

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H-Phe(4-NO2)-OH Molarity Calculator

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Preparing Stock Solutions of H-Phe(4-NO2)-OH

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.7574 mL 23.7869 mL 47.5737 mL 95.1475 mL 118.9343 mL
5 mM 0.9515 mL 4.7574 mL 9.5147 mL 19.0295 mL 23.7869 mL
10 mM 0.4757 mL 2.3787 mL 4.7574 mL 9.5147 mL 11.8934 mL
50 mM 0.0951 mL 0.4757 mL 0.9515 mL 1.9029 mL 2.3787 mL
100 mM 0.0476 mL 0.2379 mL 0.4757 mL 0.9515 mL 1.1893 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on H-Phe(4-NO2)-OH

Plant peptide hormone phytosulfokine (PSK-alpha): synthesis of new analogues and their biological evaluation.[Pubmed:15298181]

J Pept Sci. 2004 Jul;10(7):462-9.

Phytosulfokine-alpha (PSK-alpha), a sulfated growth factor (H-Tyr(SO3H)-Ile-Tyr(SO3H)-Thr-Gln-OH) universally found in both monocotyledons and dicotyledons, strongly promotes proliferation of plant cells in culture. In our studies on structure/activity relationship in PSK-alpha the synthesis of a series of analogues was performed: [H-D-Tyr(SO3H)1]- (9), [H-Phe(4-SO3H)1]- (10), [H-D-Phe(4-SO3H)1]- (11), [H-Phg(4-SO3H)1]- (12), [H-D-Phg(4-SO3H)1]- (13), H-Phe(4-NHSO2CH3)1]- (14), [H-D-Phe(4-NHSO2CH3)1]- (15), [H-Phe(4-NO2)1]- (16), [H-D-Phe(4-NO2)1]- (17), [H-Phg(4-NO2)1]- (18), [H-D-Phg(4-NO2)1]- (19), [H-Hph(4-NO2)1]- (20), [H-Phg(4-OSO3H)1]- (21), [Phe(4-NO2)3]- (22), [Phg(4-NO2)3]- (23), [Hph(4-NO2)3]- (24), [H-Phe(4-SO3H)1, Phe(4-SO3H)3]- (25) [H-Phe(4-NO2)1, Phe(4-NO2)3]- (26), [H-Phg(4-NO2)1, Phg(4-NO2)3]- (27), [H-Hph(4-NO2)1, Hph(4-NO2)3]- (28) and [Val3]- PSK-alpha (29). For modification of the PSK-alpha peptide chain the novel amino acids and their derivatives were synthesized, such as: H-L-Phg(4-SO3H)-OH (1), H-D-Phg(4-SO3H)-OH (2), Fmoc-Phg(4-SO3H)-OH (3), Fmoc-D-Phg(4-SO3H)-OH (4), Boc-Phg(4-NHSO2CH3)-OH (5), Boc-D-Phg(4-NHSO2CH3)-OH (6) Boc-Phe(4-NHSO2CH3)-OH (7), and Boc-D-Phe(4-NHSO2CH3)-OH (8). Peptides were synthesized by a solid phase method according to the Fmoc procedure on a Wang-resin. Free peptides were released from the resin by 95% TFA in the presence of EDT. All peptides were tested by competitive binding assay to the carrot membrane using 3H-labelled PSK according to the Matsubayashi et al. test.

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