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Cat.No. Product Name Information

BCC5183 Tirasemtiv Tirasemtiv is an activator of the fast skeletal muscle troponin complex.

BCC5339 Microcystin-LR Microcystin-LR inhibits protein phosphatase type 1 and type 2A (PP1 and PP2A) activities in the cytoplasm of liver cells.

BCC1958 sodium 4-pentynoate sodium 4-pentynoate is a alkynylacetate analogue; can be metabolically incorporated onto cellular proteins through biosynthetic mechanisms for profiling of acetylated proteins in diverse cell types.

BCC5555 Cyclocytidine HCl Ancitabine (hydrochloride) is an important antileukemia drugs.

BCC8057 GK921 GK921 is a transglutaminase 2 (TGase) inhibitor with an IC50 of 7.71 μM for human recombinant TGase 2. GK921

BCC3818 Monobenzone Monobenzone is a potent skin depigmenting agent. Monobenzone induces depigmentation and active human vitiligo and exhibits good potential for vitiligo research.

BCC5618 UNC 3230 UNC3230 is a potent, selective and ATP-competitive phosphatidylinositol 4-phosphate 5 kinase type 1C (PIP5K1C) inhibitor with an IC50 of ~41 nM. UNC3230 also inhibits PIP4K2C and does not inhibit any of the other lipid kinases. UNC3230 has antinociceptive and anticancer effects. UNC 3230

BCC6515 Disodium (R)-2-Hydroxyglutarate D-alpha-Hydroxyglutaric acid disodium salt is a weak competitive α-Ketoglutarate(α-KG)-dependent dioxygenase inhibitor with Ki of 10.87±1.85 mM. Ki for L-Hydroxyglutaric acid (L-2-HG) is 0.628±0.036 mM.

BCC8075 6-O-α-Maltosyl-β-cyclodextrin 6-O-α-maltosyl-β cyclodextrin (Mal-βCD) is a cellular cholesterol modifier which can form soluble inclusion complex with cholesterol and is much less cytotoxic to human erythrocytes and Caco-2 cells; a cyclodextrin derivative. 6-O-α-Maltosyl-β-cyclodextrin

BCC4711 Risedronate Risedronic acid (Risedronate ) is a pyridinyl biphosphonate which inhibits osteoclast-mediated bone resorption.

BCC3754 Clinafloxacin CI96 AM1091 Clinafloxacin(PD-127391) is a fluoroquinolone antibiotic.

BCC1956 SMND-309 SMND-309 is a metabolite of salvianolic acid B, and exhibits neuroprotective effects in cultured neurons and in permanent middle cerebral artery occlusion rats.

BCC5211 Ouabain Octahydrate Ouabain Octahydrate is an inhibitor of Na+/K+-ATPase, used for the treatment of congestive heart failure.

BCC4799 Metformin HCl Metformin hydrochloride (1,1-Dimethylbiguanide hydrochloride) inhibits the mitochondrial respiratory chain in the liver, leading to activation of AMPK, enhancing insulin sensitivity for type 2 diabetes research. Metformin hydrochloride triggers autophagy.

BCC5204 Ibandronic acid Ibandronic acid is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis.

BCC5326 Guanosine Hydrate

BCC2501 Risedronate Sodium Risedronate sodium is a pyridinyl biphosphonate which inhibits osteoclast-mediated bone resorption.

BCC5475 Aldicarb Aldicarb(OMS771; UC-21149) is a carbamate insecticide; is a cholinesterase inhibitor which prevents the breakdown of acetylcholine in the synapse.

BCC5466 Novaluron Novaluron is a chemical with pesticide properties, belonging to the class of insecticides called insect growth regulators.

BCN2710 Tranexamic acid Tranexamic acid (Transamin) is an antifibrinolytic for blocking lysine-binding sites of plasmin and elastase-derived plasminogen fragments with IC50 of 5 mM.

BCC4195 TGR5 Receptor Agonist TGR5 Receptor Agonist (CCDC), a potent TGR5(GPCR19) agonist, shows improved potency in the U2-OS cell assay (pEC50=6.8) and in melanophore cells (pEC50=7.5).

BCC4287 Dorzolamide Dorzolamide(L671152; MK507) is an anti-glaucoma agent, which is a carbonic anhydrase inhibitor.

BCC7974 TC Mps1 12 TC-Mps1-12 is a potent and selective monopolar spindle 1 (Mps1) inhibitor, with an IC50 of 6.4 nM.

BCC8059 NVS-CRF38 NVS-CRF38 is a novel corticotropin-releasing factor receptor 1 (CRF1) antagonist with low water solubility.

BCC1677 Ketone Ester BD-AcAc 2, added in diet, could elevated mean blood ketone bodies of 3.5 mm and lowered plasma glucose, insulin, and leptin in animals; ketone ester given orally would delay CNS-OT seizures in rats breathing hyperbaric oxygen.

BCN2605 Vanillin Vanillin (p-Vanillin) is a single molecule extracted from vanilla beans and also a popular odor used widely in perfume, food and medicine.

BCC7051 (-)-Terreic acid Selective inhibitor of BTK

BCC2027 Valspodar Valspodar is a selective P-glycoprotein inhibitor that has been used as an experimental cancer treatment and chemosensitizer.

BCC5446 Aurothioglucose Aurothioglucose (Gold thioglucose) is a well known active-site inhibitor of TrxR1, inhibited TrxR1 activity in HeLa cell cytosol but had no effect on the viability of the cells.

BCC5474 Cyhalofop Cyhalofop(Cyhalofop acid) is a recently registered herbicide from the aryloxyphenoxy propionate group in India to control a wide range of grass weed species at various growth stages in rice crop.

BCC4284 Acarbose sulfate Acarbose sulfate is an inhibitor of alpha glucosidase, an anti-diabetic drug.

BCC6306 ML 202 ML 202

BCC4663 Gadodiamide Gadodiamide hydrate is a gadolinium-based contrast agent used in MR imaging procedures to assist in the visualization of blood vessels.

BCC5563 URMC-099 URMC-099 is an orally bioavailable and potent mixed lineage kinase type 3 (MLK3) (IC50=14 nM) inhibitor with with excellent blood-brain barrier penetration properties.

BCN2288 Vinorelbine Tartrate Vinorelbine (ditartrate) is an anti-mitotic agent which inhibits the proliferation of Hela cells with IC50 of 1.25 nM.

BCN2346 Solasodine Solasodine(Purapuridine) is a poisonous alkaloid chemical compound that occurs in plants of the Solanaceae family.

BCC3832 Oxethazaine Oxethazaine (Oxetacaine), a precursor of phentermine acidic, is an acid-resistent and orally active analgesic agent. Oxethazaine (Oxetacaine) has the potential for the relief of pain associated with peptic ulcer disease or esophagitis.

BCC5456 BAPTA-AM BAPTA-AM is a well-known membrane permeable Ca2+ chelator. BAPTA-AM inhibits hERG channels, hKv1.3 and hKv1.5 channels in HEK 293 cells with IC50s of 1.3 μM, 1.45 μM and 1.23 μM, respectively.

BCC4015 (3S,4S)-3-(Boc-amino)-4-methylpyrrolidine

BCC4945 Ursodiol Ursodiol reduces cholesterol absorption and is used to dissolve gallstones.

BCC3719 Alendronate sodium Inhibitor of farnesyl diphosphate synthase (FPPS) and osteoclast-mediated bone resorption

BCC3690 Verteporfin Verteporfin (CL 318952) is a photosensitizer for photodynamic therapy to eliminate the abnormal blood vessels in the eye associated with conditions such as age-related macular degeneration. Verteporfin is a YAP inhibitor which disrupts YAP-TEAD interactions. Verteporfin induces cell apoptosis.Verteporfinis an autophagy inhibitor that blocks autophagy at an early stage by inhibiting autophagosome formation.

BCC8069 Tolfenpyrad Tolfenpyrad is a pesticide that was first approved in 2002 in Japan.

BCC5464 Amicarbazone Amicarbazone(BAY-MKH3586; BAY314666) is a potent inhibitor of photosynthetic electron transport via binding to the Qb domain of photosystem II (PSII); herbicide with a broad spectrum of weed control.

BCC3869 Thioridazine HCl Selective inducer of CSC differentiation; anticancer agent,Thioridazine is an antipsychotic drug, used in the treatment of schizophrenia and psychosis, shows D4 selectivity or serotonin antagonism.

BCC5445 Oxybenzone Oxybenzone(Eusolex 4360; Escalol 567) is an organic compound used in sunscreens; provides broad-spectrum ultraviolet coverage, including UVB and short-wave UVA rays.

BCC5468 Meptyldinocap Meptyldinocap (2,4-DNOPC) is a novel powdery mildew (Erysiphe necator) fungicide which shows protectant and post-infective activities.

BCC3768 Diphenylpyraline HCl Diphenylpyraline hydrochloride (4-Diphenylmethoxy-1-methylpiperidine hydrochloride) is a first-generation antihistamine with anticholinergic effects, acts as a dopamine reuptake inhibitor, shows to be useful in the treatment of Parkinsonism.

BCC5333 (Z)-Pugnac

BCC6491 3-Indolebutyric acid (IBA) Indole-3-butyric acid (3-indolebutyric acid; IBA) is a plant growth auxin and a good rooting agent. It can promote herbs and woody ornamental plant rooting and used for improving fruit rate.

BCC4872 Trichlormethiazide Trichlormethiazide is a thiazide diuretic with properties similar to those of hydrochlorothiazide.

BCC5616 3PO 3PO

BCC8053 GSK2194069 GSK2194069 is a potent and specific inhibitor of the β-ketoacyl reductase (KR) activity of hFAS with an IC50 of 7.7 ± 4.1 nM in an assay detecting released CoA.

BCC8064 PF 1022A PF 1022A is a N-methylated cyclooctadepsipeptides (CODPs) with strong anthelmintic properties; acts as an ionophore.

BCC7972 LIMKi 3 BMS-5 (LIMKi 3) is a potent LIMK inhibitor with IC50s of 7 nM and 8 nM for LIMK1 and LIMK2, respectively. LIMKi 3

BCC5188 Methylcobalamin Methylcobalamin (CH3-B12), a cobalamin, is a form of vitamin B12.

BCC5462 kb-NB77-78 kb-NB77-78 is an analogue of CID797718, but shows no PKD inhibitory activity.

BCC1891 Retinyl glucoside Retinyl-β-D-glucoside is a naturally occurring and biologically active metabolites of vitamin A, which are found in fish and mammals.

BCC5525 BRD4770 BRD4770 is a histone methyltransferase G9a inhibitor. BRD4770 reduces di- and trimethylation of lysine 9 on histone H3 (H3K9) with an EC50 of 5 µM, and has less or little effect toward H3K27me3, H3K36me3, H3K4me3, and H3K79me3. BRD4770 can activate the ataxia telangiectasia mutated (ATM) pathway and induce cell senescence. BRD4770

BCC5198 Vigabatrin Hydrochloride Vigabatrin (Hydrochloride) (γ-Vinyl-GABA; Sabril) is a structural analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) that irreversibly inhibits the catabolism of GABA by GABA transaminase.

BCC1086 7-Methoxycoumarin-4-acetyl-P-L-G-L-β-(2,4-dinitrophenylamino)A-R amide

BCC6317 ML 281 ML281 is a potent and selective STK33 inhibitor with IC50 of 14 nM. ML 281

BCC6268 PF 06465469 PF-06465469 is a covalent inhibitor of ITK with an IC50 of 2 nM.

BCC5442 5S rRNA modificator 5S rRNA modificator is a suitable electrophile for 2’-hydroxyl acylation on structured RNA molecules, yielding accurate structural information comparable to that obtained with existing probes; 5S rRNA RNA modification.

BCC1315 9-Dihydro-13-acetylbaccatin III 9-Dihydro-13-acetylbaccatin III (9-DHAB III) is an intermediate for taxol analog preparations.

BCC6203 A 484954 A-484954 is a highly selective eukaryotic elongationfactor-2 (eEF2) inhibitor, with an IC50 of 280 nM.

BCC8061 ML216 ML216 (CID-49852229) is a potent, selective and cell permeable inhibitor of the DNA unwinding activity of BLM helicase with IC50s of 2.98 μM and 0.97 μM for BLMfull-length and BLM636-1298, respectively. ML216 inhibits ssDNA-dependent ATPase activity of BLM with a Ki of 1.76 µM. Antitumor avtivity. ML216

BCC5336 (Arg)9 peptide (Arg)9 (Nona-L-arginine;Peptide R9) is a cell-penetrating peptide; exhibits neuroprotective activity with an IC50 of 0.78 μM in the glutamic acid model.

BCC1546 Elacridar Elacridar is a potent P-glycoprotein (Pgp) and BCRP inhibitor.

BCC1547 Elacridar hydrochloride Elacridar hydrochloride (GF120918A) is a P-glycoprotein inhibitor, and has been used both in vitro and in vivo as a tool inhibitor of P-glycoprotein (Pgp) to investigate the role of transporters in the disposition of various test molecules.

BCC5493 CB-839 Telaglenastat (CB-839) is a first-in-class, selective, reversible and orally active glutaminase 1 (GLS1) inhibitor. Telaglenastat selectively inhibits GLS1 splice variants KGA (kidney-type glutaminase) and GAC (glutaminase C) compared to GLS2. The IC50s are 23 nM and 28 nM for endogenous glutaminase in mouse kidney and brain, respectively. Telaglenastat inudces autophagy and has antitumor activity. CB-839

BCC5343 MSDC-0160 MSDC 0160 (Mitoglitazone) is a mitochondrial target of thiazolidinediones (mTOT)-modulating insulin sensitizer and a modulator of mitochondrial pyruvate carrier (MPC). MSDC 0160 is a thiazolidinedione (TZD) with antidiabetic and neuroprotective activities. MSDC 0160 has the potential for Alzheimer′s disease. MSDC-0160

BCC5196 R-(-)-Deprenyl hydrochloride R-(-)-Deprenyl Hydrochloride is a selective inhibitor of monoamine oxidase B (MAO-B).

BCC5104 Atglistatin Atglistatin is a selective adipose triglyceride lipase (ATGL) inhibitor which inhibits lipolysis with an IC50 of 0.7 μM in vitro.

BCC4787 ID-8 ID-8 is a DYRK inhibitor, and sustains embryonic stem cell self-renewal in long-term culture. ID-8

BCC3868 Thiabendazole Thiabendazole inhibites the mitochondrial helminth-specific enzyme, fumarate reductase, with anthelminthic property.

BCC3739 Bismuth Subsalicylate Bismuth Subsalicylate is the active ingredient in Pepto-Bismol and inhibits prostaglandin G/H Synthase 1/2.

BCC4876 UNC2250 UNC2250 is a potent and selective Mer inhibitor with an IC50 of 1.7 nM, about 160- and 60-fold selectivity over the closely related kinases Axl/Tyro3. UNC2250

BCC5197 Zaleplon

BCC5382 XEN445 XEN445 is a potent and selective EL inhibitor(IC50=0.237 uM), that showed good ADME and PK properties, and demonstrated in vivo efficacy in raising plasma HDLc concentrations in mice. XEN445

BCC5411 7-Epi-docetaxel 7-Epi-10-oxo-docetaxel (Docetaxel Impurity C; 7-Epitaxotere) is a impurity of docetaxel.

BCC5189 Travoprost Travoprost is used to treat glaucoma and ocular hypertension.

BCC5533 Chitinase-IN-1 Chitinase-IN-1 is a insect chitinase and N- acetyl hexosaminidase inhibitor and pesticide; 50 uM/20 uM compound concentration's inhibitory percentage are 75%/67% for chitinase/N- acetyl-hexosaminidase respectively.

BCC5534 Chitinase-IN-2 Chitinase-IN-2 is a insect chitinase and N- acetyl hexosaminidase inhibitor and pesticide; 50 uM/20uM compound concentration's inhibitory percentage are 98%/92% for chitinase/N- acetyl-hexosaminidase respectively.

BCC8073 Pyraclonil Pyraclonil is a herbicide agent.

BCC4028 Mc-Val-Cit-PABC-PNP Mc-Val-Cit-PABC-PNP is a cathepsin cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

BCC2063 X-NeuNAc X-Neu5Ac is a substrate for chromogenic assay of neuraminidase activity in bacterial expression systems; with a Km of 0.89 mM for neuraminidase.

BCC5545 Ro 48-8071 Ro 48-8071 is an inhibitor of OSC(Oxidosqualene cyclase; IC50=6.5 nM) that has low-density lipoprotein (LDL) cholesterol lowering activity.

BCC1095 Dimesna Dimesna is an protective agent used to decrease urotoxicity. Dimesna

BCC5410 7-Epi-10-oxo-docetaxel 7-Epi-10-oxo-docetaxel (Docetaxel Impurity 2) is a impurity of docetaxel detected by high performance liquid chromatography (HPLC).

BCC5471 Bethoxazin Bethoxazin(Bethoguard) is a new broad spectrum industrial microbicide with applications in material and coating preservation.

BCC5522 Auristatin F Auristatin F is a potent cytotoxin. Auristatin F, a potent microtubule inhibitor and vascular damaging agent (VDA), can be used in antibody-drug conjugates (ADC).

BCC5476 Aldicarb sulfone Aldicarb sulfone(Temik sulfone) is a carbamate insecticide; is a cholinesterase inhibitor which prevents the breakdown of acetylcholine in the synapse.

BCC5409 10-Oxo Docetaxel 10-Oxo Docetaxel (Docetaxel Impurity 1) is a novel taxoid having remarkable anti-tumor properties and a Docetaxel intermediate.

BCC5470 Benoxafos Benoxafos (HOE 2910) is an insecticide.

BCC4955 NXY-059 Disufenton sodium (NXY-059) is the disulfonyl derivative of the neuroprotective spin trap phenylbutynitrone(PBN), both NXY-059, its parent PBN and their hydrolysis/oxidation product MNT are very powerful scavengers of free radicals. NXY-059

BCC5400 TAPI-1 TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors. TAPI-1

BCC3743 Calcium Gluceptate NSC 42196 is an endogenous metabolite.

BCC5386 Afobazole Fabomotizole is an anxiolytic drug; produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions.

BCC2009 Tonabersat Tonabersat is a gap-junction modulator.

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