7-Epi-10-oxo-docetaxelCAS# 162784-72-7 |
Related Products
- NSC 23766
Catalog No.:BCC1149
CAS No.:1177865-17-6
- Zoledronic Acid
Catalog No.:BCC1067
CAS No.:118072-93-8
- EHop-016
Catalog No.:BCC5022
CAS No.:1380432-32-5
- ZCL278
Catalog No.:BCC3665
CAS No.:587841-73-4
Quality Control & MSDS
3D structure
Package In Stock
Number of papers citing our products
| Cas No. | 162784-72-7 | SDF | Download SDF |
| PubChem ID | 9940648 | Appearance | Powder |
| Formula | C43H51NO14 | M.Wt | 805.86 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Synonyms | Docetaxel Impurity | ||
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | [(1S,2S,3R,4S,7R,9R,10S,15S)-4-acetyloxy-1,9-dihydroxy-15-[(2R,3S)-2-hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]oxy-10,14,17,17-tetramethyl-11,12-dioxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate | ||
| SMILES | CC1=C2C(=O)C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C | ||
| Standard InChIKey | ZOLQDWANVNOXBK-JSBGVCCUSA-N | ||
| Standard InChI | InChI=1S/C43H51NO14/c1-22-26(55-37(51)32(48)30(24-15-11-9-12-16-24)44-38(52)58-39(3,4)5)20-43(53)35(56-36(50)25-17-13-10-14-18-25)33-41(8,34(49)31(47)29(22)40(43,6)7)27(46)19-28-42(33,21-54-28)57-23(2)45/h9-18,26-28,30,32-33,35,46,48,53H,19-21H2,1-8H3,(H,44,52)/t26-,27+,28+,30-,32+,33-,35-,41+,42-,43+/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
7-Epi-10-oxo-docetaxel Dilution Calculator
7-Epi-10-oxo-docetaxel Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.2409 mL | 6.2046 mL | 12.4091 mL | 24.8182 mL | 31.0228 mL |
| 5 mM | 0.2482 mL | 1.2409 mL | 2.4818 mL | 4.9636 mL | 6.2046 mL |
| 10 mM | 0.1241 mL | 0.6205 mL | 1.2409 mL | 2.4818 mL | 3.1023 mL |
| 50 mM | 0.0248 mL | 0.1241 mL | 0.2482 mL | 0.4964 mL | 0.6205 mL |
| 100 mM | 0.0124 mL | 0.062 mL | 0.1241 mL | 0.2482 mL | 0.3102 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
7-Epi-10-oxo-docetaxel (Docetaxel Impurity D) is a impurity of docetaxel detected by high performance liquid chromatography (HPLC).
References:
[1]. Vasu Dev R, et al. Isolation and characterization of impurities in docetaxel. J Pharm Biomed Anal. 2006 Feb 24;40(3):614-22.
Featured Products
- LJI308
Catalog No.:BCC6538
CAS No.:1627709-94-7
- PFI-2
Catalog No.:BCC5561
CAS No.:1627676-59-8
- Yunnancoronarin A
Catalog No.:BCN1723
CAS No.:162762-93-8
- WAY-100635
Catalog No.:BCC2053
CAS No.:162760-96-5
- Anemarrhena B
Catalog No.:BCN7592
CAS No.:1627521-95-2
- LDN-214117
Catalog No.:BCC5528
CAS No.:1627503-67-6
- AZD8186
Catalog No.:BCC6470
CAS No.:1627494-13-6
- 1-Hydroxy-2-prenylnaphthalene
Catalog No.:BCN1722
CAS No.:16274-34-3
- 3,4-Dihydro-2,2-dimethyl-2H-naphtho[1,2-b]pyran
Catalog No.:BCN1539
CAS No.:16274-33-2
- Kaempferol tetraacetate
Catalog No.:BCN1721
CAS No.:16274-11-6
- 6-Deoxyjacareubin
Catalog No.:BCN6573
CAS No.:16265-56-8
- HQL 79
Catalog No.:BCC7703
CAS No.:162641-16-9
New Products
- IEM 1754 dihydrobroMide
Catalog No.:BCC5049
CAS No.:162831-31-4
- 2,3,9,10-Tetrahydroxyberberine
Catalog No.:BCN3550
CAS No.:162854-37-7
- Polygalasaponin V
Catalog No.:BCN2790
CAS No.:162857-65-0
- Polygalaxanthone III
Catalog No.:BCN2354
CAS No.:162857-78-5
- Antibiotic AB 4015B
Catalog No.:BCN1826
CAS No.:162857-79-6
- (S)-3,5-DHPG
Catalog No.:BCC6802
CAS No.:162870-29-3
- Kaempferol-7-O-D-glucopyranoside
Catalog No.:BCN2296
CAS No.:16290-07-6
- 3,4-Dihydroxybenzylamine Hydrobromide
Catalog No.:BCC8280
CAS No.:16290-26-9
- Bis(4-bromophenyl)amine
Catalog No.:BCC8883
CAS No.:16292-17-4
- K-Ras G12C-IN-1
Catalog No.:BCC5538
CAS No.:1629265-17-3
- K-Ras G12C-IN-2
Catalog No.:BCC5539
CAS No.:1629267-75-9
- K-Ras G12C-IN-3
Catalog No.:BCC5540
CAS No.:1629268-19-4
Isolation and characterization of degradation impurities in docetaxel drug substance and its formulation.[Pubmed:17126518]
J Pharm Biomed Anal. 2007 Mar 12;43(4):1228-35.
The degradation of docetaxel drug substance and its injection formulation has been investigated. The majority of impurities were observed in a base degradation study and all five degradation products were characterized. These impurities were isolated, enriched and were subjected to mass and NMR spectral studies. Based on the spectral data, these were characterized as 10-deacetyl baccatin III, 7-epi-10-deacetyl baccatin III, 7-epi-10-oxo-10-deacetyl baccatin III, 7-epi docetaxel and 7-Epi-10-oxo-docetaxel, respectively. The last two impurities were also detected in the stability study of docetaxel formulation. Out of these degradation impurities two substances have been previously identified while the other three previously unreported.
7-Epi-10-oxo-docetaxel (Docetaxel Impurity 2) is a impurity of docetaxel detected by high performance liquid chromatography (HPLC).
7-Epi-10-oxo-docetaxel,162784-72-7,Docetaxel Impurity,Natural Products,Others, buy 7-Epi-10-oxo-docetaxel , 7-Epi-10-oxo-docetaxel supplier , purchase 7-Epi-10-oxo-docetaxel , 7-Epi-10-oxo-docetaxel cost , 7-Epi-10-oxo-docetaxel manufacturer , order 7-Epi-10-oxo-docetaxel , high purity 7-Epi-10-oxo-docetaxel
