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N-Debenzoyl-N-(tert-butoxycarbonyl)taxol

CAS# 125354-16-7

N-Debenzoyl-N-(tert-butoxycarbonyl)taxol

Catalog No. BCN1592----Order now to get a substantial discount!

Product Name & Size Price Stock
N-Debenzoyl-N-(tert-butoxycarbonyl)taxol: 5mg Please Inquire In Stock
N-Debenzoyl-N-(tert-butoxycarbonyl)taxol: 10mg Please Inquire In Stock
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Quality Control of N-Debenzoyl-N-(tert-butoxycarbonyl)taxol

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Chemical structure

N-Debenzoyl-N-(tert-butoxycarbonyl)taxol

3D structure

Chemical Properties of N-Debenzoyl-N-(tert-butoxycarbonyl)taxol

Cas No. 125354-16-7 SDF Download SDF
PubChem ID 147895 Appearance Powder
Formula C45H55NO15 M.Wt 849.92
Type of Compound Diterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)OC(=O)C
Standard InChIKey LEMYAXKYCOBYOJ-OAGWZNDDSA-N
Standard InChI InChI=1S/C45H55NO15/c1-23-28(58-39(53)33(50)32(26-16-12-10-13-17-26)46-40(54)61-41(4,5)6)21-45(55)37(59-38(52)27-18-14-11-15-19-27)35-43(9,29(49)20-30-44(35,22-56-30)60-25(3)48)36(51)34(57-24(2)47)31(23)42(45,7)8/h10-19,28-30,32-35,37,49-50,55H,20-22H2,1-9H3,(H,46,54)/t28-,29-,30+,32-,33+,34+,35-,37-,43+,44-,45+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of N-Debenzoyl-N-(tert-butoxycarbonyl)taxol

The barks of Taxus chinensis (Pilger) Rehd.

Biological Activity of N-Debenzoyl-N-(tert-butoxycarbonyl)taxol

Description1. 10-Acetyldocetaxel(N-Debenzoyl-N-(tert-butoxycarbonyl)taxol ) has selective high-activity and high-efficiency functions on treating metastatic colon cancer and stomach cancer.

N-Debenzoyl-N-(tert-butoxycarbonyl)taxol Dilution Calculator

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N-Debenzoyl-N-(tert-butoxycarbonyl)taxol Molarity Calculator

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Preparing Stock Solutions of N-Debenzoyl-N-(tert-butoxycarbonyl)taxol

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.1766 mL 5.8829 mL 11.7658 mL 23.5316 mL 29.4145 mL
5 mM 0.2353 mL 1.1766 mL 2.3532 mL 4.7063 mL 5.8829 mL
10 mM 0.1177 mL 0.5883 mL 1.1766 mL 2.3532 mL 2.9415 mL
50 mM 0.0235 mL 0.1177 mL 0.2353 mL 0.4706 mL 0.5883 mL
100 mM 0.0118 mL 0.0588 mL 0.1177 mL 0.2353 mL 0.2941 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on N-Debenzoyl-N-(tert-butoxycarbonyl)taxol

10-acetyldocetaxel and application thereof

CN 103980232 A[P]. 2014.

The invention relates to 10-acetyldocetaxel(N-Debenzoyl-N-(tert-butoxycarbonyl)taxol) and functions thereof on treating metastatic colon cancer and stomach cancer. By using paclitaxel and docetaxel as reference medicines, in-vitro and in-vivo comparative studies accidentally detect that the 10-acetyldocetaxel(N-Debenzoyl-N-(tert-butoxycarbonyl)taxol) has selective high-activity and high-efficiency functions on treating metastatic colon cancer and stomach cancer.

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