Pachysamine MCAS# 1253202-75-3 |
Quality Control & MSDS
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| Cas No. | 1253202-75-3 | SDF | Download SDF |
| PubChem ID | 46939340 | Appearance | Powder |
| Formula | C28H44N2O2 | M.Wt | 440.67 |
| Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | N-[(5R,8S,9S,10R,13S,14S,17S)-17-[(1S)-1-(dimethylamino)ethyl]-10,13-dimethyl-4-oxo-1,5,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-yl]-3-methylbut-2-enamide | ||
| SMILES | CC(C1CCC2C1(CCC3C2CCC4C3(CC=C(C4=O)NC(=O)C=C(C)C)C)C)N(C)C | ||
| Standard InChIKey | FPBGDMGTAHIUMI-ULXDPTIJSA-N | ||
| Standard InChI | InChI=1S/C28H44N2O2/c1-17(2)16-25(31)29-24-13-15-28(5)22-12-14-27(4)20(18(3)30(6)7)10-11-21(27)19(22)8-9-23(28)26(24)32/h13,16,18-23H,8-12,14-15H2,1-7H3,(H,29,31)/t18-,19-,20+,21-,22-,23-,27+,28+/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The roots of Sarcococca ruscifolia.
| Description | 1. Pachysamine M shows inhibitory activities against multiple types of cancer cells. |
Pachysamine M Dilution Calculator
Pachysamine M Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.2693 mL | 11.3464 mL | 22.6927 mL | 45.3854 mL | 56.7318 mL |
| 5 mM | 0.4539 mL | 2.2693 mL | 4.5385 mL | 9.0771 mL | 11.3464 mL |
| 10 mM | 0.2269 mL | 1.1346 mL | 2.2693 mL | 4.5385 mL | 5.6732 mL |
| 50 mM | 0.0454 mL | 0.2269 mL | 0.4539 mL | 0.9077 mL | 1.1346 mL |
| 100 mM | 0.0227 mL | 0.1135 mL | 0.2269 mL | 0.4539 mL | 0.5673 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Pregnane alkaloids from Sarcococca ruscifolia and their cytotoxic activity.
Phytochemistry Letters, 2015, 14:31-34.
Six pregnane alkaloids were isolated from the root of Sarcococca ruscifolia. The structures of three new alkaloids, namely, sarcorucinine E-G (1-3), were elucidated using spectroscopic methods, while three known alkaloids, namely, epipachysamine D, Pachysamine M, and sarcovagine D, were identified by comparing their spectral data with those of the compounds reported earlier. All compounds were evaluated for their inhibitory activities against multiple types of cancer cells.
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