Kaempferol tetraacetateCAS# 16274-11-6 |
Quality Control & MSDS
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| Cas No. | 16274-11-6 | SDF | Download SDF |
| PubChem ID | 14130926 | Appearance | Powder |
| Formula | C23H18O10 | M.Wt | 454.4 |
| Type of Compound | Flavonoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | [4-(3,5,7-triacetyloxy-4-oxochromen-2-yl)phenyl] acetate | ||
| SMILES | CC(=O)OC1=CC=C(C=C1)C2=C(C(=O)C3=C(C=C(C=C3O2)OC(=O)C)OC(=O)C)OC(=O)C | ||
| Standard InChIKey | UXAYHERJWMTSFV-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C23H18O10/c1-11(24)29-16-7-5-15(6-8-16)22-23(32-14(4)27)21(28)20-18(31-13(3)26)9-17(30-12(2)25)10-19(20)33-22/h5-10H,1-4H3 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1. Kaempferol tetraacetate exhibits significant cytotoxicity in vitro against three human cell lines HL-60, U937 and SK-MEL-1. 2. Kaempferol tetraacetate is a potent antiplatelet agent. |
| Targets | Antifection |
Kaempferol tetraacetate Dilution Calculator
Kaempferol tetraacetate Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.2007 mL | 11.0035 mL | 22.007 mL | 44.0141 mL | 55.0176 mL |
| 5 mM | 0.4401 mL | 2.2007 mL | 4.4014 mL | 8.8028 mL | 11.0035 mL |
| 10 mM | 0.2201 mL | 1.1004 mL | 2.2007 mL | 4.4014 mL | 5.5018 mL |
| 50 mM | 0.044 mL | 0.2201 mL | 0.4401 mL | 0.8803 mL | 1.1004 mL |
| 100 mM | 0.022 mL | 0.11 mL | 0.2201 mL | 0.4401 mL | 0.5502 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Selective methylation of kaempferol via benzylation and deacetylation of kaempferol acetates.[Pubmed:25815082]
Beilstein J Org Chem. 2015 Feb 25;11:288-93.
A strategy for selective mono-, di- and tri-O-methylation of kaempferol, predominantly on the basis of selective benzylation and controllable deacetylation of kaempferol acetates, was developed. From the selective deacetylation and benzylation of Kaempferol tetraacetate (1), 3,4',5,-tri-O-acetylkaempferol (2) and 7-O-benzyl-3,4'5,-tri-O-acetylkaempferol (8) were obtained, respectively. By controllable deacetylation and followed selective or direct methylation of these two intermediates, eight O-methylated kaempferols were prepared with 51-77% total yields from kaempferol.
Cytotoxic activities of flavonoid glycoside acetates from Consolida oliveriana.[Pubmed:18214815]
Planta Med. 2008 Feb;74(2):171-4.
The flavonoids kaempferol, quercetin, trifolin, hyperoside 2''- and 6''- acetates, 7-glucotrifolin, biorobin and robinin were isolated from the aerial parts of Consolida oliveriana. Their derivatives Kaempferol tetraacetate, quercetin pentaacetate, trifolin heptaacetate and hyperoside octaacetate exhibited significant cytotoxicity IN VITRO against three human cell lines HL-60, U937 and SK-MEL-1 while hyperoside 2''-acetate, hyperoside-6''-acetate, glucotrifolin decaacetate and heptamethyltrifolin were inactive.
Antiplatelet effects and vasorelaxing action of some constituents of Formosan plants.[Pubmed:8350094]
J Nat Prod. 1993 Jun;56(6):929-34.
Various xanthones as well as quercetin have been shown to exhibit antiplatelet activity. A series of anthraquinones analogues structurally related to xanthones and a series of quercetin-related compounds were tested for their antiplatelet effects. Emodin, frangulin B, Kaempferol tetraacetate, quercetin-3-O-galactoside octaacetate, rhamnazin triacetate, and rhamnetin tetraacetate were found to be potent antiplatelet agents, and 1,8-dihydroxy-6-methoxy-3-methylanthraquinone 8-O-rhamnosyl-(1-->2)-glucoside, rhamnustrioside undecaacetate, rutin decaacetate, and quercetin-3-O-(6-O-alpha-L-arabinopyranosyl)-beta-D-galactopyranos ide decaacetate showed significant antiplatelet effects. Quercetin showed vasorelaxing action in rat thoracic aorta.
