Diphenylpyraline HClCAS# 132-18-3 |
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| Cas No. | 132-18-3 | SDF | Download SDF |
| PubChem ID | 66063 | Appearance | Powder |
| Formula | C19H24ClNO | M.Wt | 317.85 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Synonyms | 4-Diphenylmethoxy-1-methylpiperidine hydrochloride | ||
| Solubility | H2O : 100 mg/mL (314.61 mM; Need ultrasonic) DMSO : ≥ 100 mg/mL (314.61 mM) *"≥" means soluble, but saturation unknown. | ||
| Chemical Name | 4-benzhydryloxy-1-methylpiperidine;hydrochloride | ||
| SMILES | CN1CCC(CC1)OC(C2=CC=CC=C2)C3=CC=CC=C3.Cl | ||
| Standard InChIKey | LPRLDRXGWKXRMQ-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C19H23NO.ClH/c1-20-14-12-18(13-15-20)21-19(16-8-4-2-5-9-16)17-10-6-3-7-11-17;/h2-11,18-19H,12-15H2,1H3;1H | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Diphenylpyraline Hcl is a first-generation antihistamine with anticholinergic effects, acts as a dopamine reuptake inhibitor, shows to be useful in the treatment of Parkinsonism. |
Diphenylpyraline HCl Dilution Calculator
Diphenylpyraline HCl Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.1461 mL | 15.7307 mL | 31.4614 mL | 62.9228 mL | 78.6535 mL |
| 5 mM | 0.6292 mL | 3.1461 mL | 6.2923 mL | 12.5846 mL | 15.7307 mL |
| 10 mM | 0.3146 mL | 1.5731 mL | 3.1461 mL | 6.2923 mL | 7.8653 mL |
| 50 mM | 0.0629 mL | 0.3146 mL | 0.6292 mL | 1.2585 mL | 1.5731 mL |
| 100 mM | 0.0315 mL | 0.1573 mL | 0.3146 mL | 0.6292 mL | 0.7865 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Diphenylpyraline is a first-generation antihistamine with anticholinergic effects of the diphenylpiperidine class.
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Simultaneous estimation of phenylpropanolamine HCl, guaiphenesin and diphenylpyraline HCl in syrups by LC.[Pubmed:11108536]
J Pharm Biomed Anal. 2000 Dec;24(1):25-31.
A simple, precise and accurate HPLC method was developed for the simultaneous estimation of phenyl-propanolamine HCl, guaiphenesin and Diphenylpyraline HCl in syrup. The method was carried out on a Shimpak C8 column with a mobile phase consisting of acetonitrile-triethylamine (pH adjusted to 3.5 using orthophosphoric acid; 0.5%), (35:65, v/v) at a flow rate of 1.2 ml min(-1). Detection was carried out at 210 nm. Diphenhydramine was used as internal standard. The validation of the method was also carried out.
Diphenylpyraline hydrochloride (4-Diphenylmethoxy-1-methylpiperidine hydrochloride) is a first-generation antihistamine with anticholinergic effects, acts as a dopamine reuptake inhibitor, shows to be useful in the treatment of Parkinsonism.
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