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2-Hydroxyethyl Salicylate

CAS# 87-28-5

2-Hydroxyethyl Salicylate

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Quality Control of 2-Hydroxyethyl Salicylate

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Chemical structure

2-Hydroxyethyl Salicylate

3D structure

Chemical Properties of 2-Hydroxyethyl Salicylate

Cas No. 87-28-5 SDF Download SDF
PubChem ID 6880 Appearance Colorless liquid (> 20°c)
Formula C9H10O4 M.Wt 182.18
Type of Compound Phenols Storage Desiccate at -20°C
Synonyms 2-Hydroxyethyl 2-hydroxybenzoate
Solubility DMSO : 160 mg/mL (878.30 mM; Need ultrasonic and warming)
Chemical Name 2-hydroxyethyl 2-hydroxybenzoate
SMILES C1=CC=C(C(=C1)C(=O)OCCO)O
Standard InChIKey LVYLCBNXHHHPSB-UHFFFAOYSA-N
Standard InChI InChI=1S/C9H10O4/c10-5-6-13-9(12)7-3-1-2-4-8(7)11/h1-4,10-11H,5-6H2
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Biological Activity of 2-Hydroxyethyl Salicylate

Description1. Carbamazepine, (5H-dibenz[b,f]azepine)-5-carboxamide, a potent anticonvulsant drug.

2-Hydroxyethyl Salicylate Dilution Calculator

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2-Hydroxyethyl Salicylate Molarity Calculator

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Preparing Stock Solutions of 2-Hydroxyethyl Salicylate

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 5.4891 mL 27.4454 mL 54.8908 mL 109.7815 mL 137.2269 mL
5 mM 1.0978 mL 5.4891 mL 10.9782 mL 21.9563 mL 27.4454 mL
10 mM 0.5489 mL 2.7445 mL 5.4891 mL 10.9782 mL 13.7227 mL
50 mM 0.1098 mL 0.5489 mL 1.0978 mL 2.1956 mL 2.7445 mL
100 mM 0.0549 mL 0.2745 mL 0.5489 mL 1.0978 mL 1.3723 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 2-Hydroxyethyl Salicylate

[Clinical trial of the new percutaneously active antirheumatic etofenamate. Summarising report (author's transl)].[Pubmed:144509]

Arzneimittelforschung. 1977;27(6B):1357-63.

2-(2-Hydroxyethoxy)ethyl-N-(a,a,a-trifluoro-m-tolyl)anthranilate (etofenamate, Rheumon Gel), a percutaneously active antirheumatic containing etofenamate as active principle has been subjected to clinical studies in both hospitalized and out-patients in various types of rheumatic disease. These trials included double-blind studies against placebo gel, controlled comparative studies against two topical commercial products (ointmentI: combination of 2-Hydroxyethyl Salicylate and p-menthan-3-ol; ointment II: 3,5-dioxo-1,2-diphenyl-4-n-butylpyrazolidine) and open trials for efficacy and tolerance. Of the 760 patients taking part in the trials, 556 were treated with Rheumon Gel.

Description

Glycol salicylate is a derivative of salicylic acid and can be used to improve the aesthetic appearance of the skin, extracted from patent US 20150148320 A1.

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