Ugaxanthone

CAS# 13179-11-8

Ugaxanthone

2D Structure

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3D structure

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Ugaxanthone

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Chemical Properties of Ugaxanthone

Cas No. 13179-11-8 SDF Download SDF
PubChem ID 5321880 Appearance Powder
Formula C18H16O6 M.Wt 328.32
Type of Compound Xanthones Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 1,3,5,6-tetrahydroxy-4-(3-methylbut-2-enyl)xanthen-9-one
SMILES CC(=CCC1=C(C=C(C2=C1OC3=C(C2=O)C=CC(=C3O)O)O)O)C
Standard InChIKey ZZUFNBISWJNCEE-UHFFFAOYSA-N
Standard InChI InChI=1S/C18H16O6/c1-8(2)3-4-9-12(20)7-13(21)14-15(22)10-5-6-11(19)16(23)18(10)24-17(9)14/h3,5-7,19-21,23H,4H2,1-2H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Ugaxanthone

The herbs of Symphonia globulifera L.

Biological Activity of Ugaxanthone

DescriptionUgaxanthone is a natural product from Symphonia globulifera L.

Protocol of Ugaxanthone

Structure Identification
Nat Prod Commun. 2009 Jun;4(6):803-8.

Globulixanthone F, a new polyoxygenated xanthone with an isoprenoid group and two antimicrobial biflavonoids from the stem bark of Symphonia globulifera.[Pubmed: 19634326]


METHODS AND RESULTS:
Bioassay-guided fractionation of the stem bark of Symphonia globulifera has yielded three known xanthones, Ugaxanthone (1), mbarraxanthone (2) and gentisein (3), two biflavonoid derivatives named GB2 (4) and manniflavanone GB3 (5), and one new polyoxygenated xanthone with an isoprenoid group, named globulixanthone F (6). The structures of these compounds were elucidated by means of spectroscopic methods.
CONCLUSIONS:
The spectral data of 1 and 2 are reported here for the first time, as well as the antimicrobial activity of globulixanthone F against a range of microorganisms. We also report the total synthesis of the xanthone skeleton.

Ugaxanthone Dilution Calculator

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Ugaxanthone Molarity Calculator

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Preparing Stock Solutions of Ugaxanthone

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.0458 mL 15.229 mL 30.4581 mL 60.9162 mL 76.1452 mL
5 mM 0.6092 mL 3.0458 mL 6.0916 mL 12.1832 mL 15.229 mL
10 mM 0.3046 mL 1.5229 mL 3.0458 mL 6.0916 mL 7.6145 mL
50 mM 0.0609 mL 0.3046 mL 0.6092 mL 1.2183 mL 1.5229 mL
100 mM 0.0305 mL 0.1523 mL 0.3046 mL 0.6092 mL 0.7615 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Ugaxanthone

Globulixanthone F, a new polyoxygenated xanthone with an isoprenoid group and two antimicrobial biflavonoids from the stem bark of Symphonia globulifera.[Pubmed:19634326]

Nat Prod Commun. 2009 Jun;4(6):803-8.

Bioassay-guided fractionation of the stem bark of Symphonia globulifera has yielded three known xanthones, Ugaxanthone (1), mbarraxanthone (2) and gentisein (3), two biflavonoid derivatives named GB2 (4) and manniflavanone GB3 (5), and one new polyoxygenated xanthone with an isoprenoid group, named globulixanthone F (6). The structures of these compounds were elucidated by means of spectroscopic methods. The spectral data of 1 and 2 are reported here for the first time, as well as the antimicrobial activity of globulixanthone F against a range of microorganisms. We also report the total synthesis of the xanthone skeleton.

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