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Aldicarb sulfone

CAS# 1646-88-4

Aldicarb sulfone

2D Structure

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Aldicarb sulfone

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Chemical Properties of Aldicarb sulfone

Cas No. 1646-88-4 SDF Download SDF
PubChem ID 9570093 Appearance Powder
Formula C7H14N2O4S M.Wt 222.26
Type of Compound N/A Storage Desiccate at -20°C
Solubility DMSO : ≥ 34 mg/mL (152.97 mM)
*"≥" means soluble, but saturation unknown.
Chemical Name [(E)-(2-methyl-2-methylsulfonylpropylidene)amino] N-methylcarbamate
SMILES CC(C)(C=NOC(=O)NC)S(=O)(=O)C
Standard InChIKey YRRKLBAKDXSTNC-WEVVVXLNSA-N
Standard InChI InChI=1S/C7H14N2O4S/c1-7(2,14(4,11)12)5-9-13-6(10)8-3/h5H,1-4H3,(H,8,10)/b9-5+
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Biological Activity of Aldicarb sulfone

DescriptionAldicarb sulfone(Temik sulfone) is a carbamate insecticide; is a cholinesterase inhibitor which prevents the breakdown of acetylcholine in the synapse.

Aldicarb sulfone Dilution Calculator

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Preparing Stock Solutions of Aldicarb sulfone

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.4992 mL 22.4962 mL 44.9924 mL 89.9847 mL 112.4809 mL
5 mM 0.8998 mL 4.4992 mL 8.9985 mL 17.9969 mL 22.4962 mL
10 mM 0.4499 mL 2.2496 mL 4.4992 mL 8.9985 mL 11.2481 mL
50 mM 0.09 mL 0.4499 mL 0.8998 mL 1.7997 mL 2.2496 mL
100 mM 0.045 mL 0.225 mL 0.4499 mL 0.8998 mL 1.1248 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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Background on Aldicarb sulfone

Aldicarb sulfone(Temik sulfone) is a carbamate insecticide; is a cholinesterase inhibitor which prevents the breakdown of acetylcholine in the synapse.

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References on Aldicarb sulfone

Determination of aldicarb, aldicarb sulfoxide and aldicarb sulfone in some fruits and vegetables using high-performance liquid chromatography-atmospheric pressure chemical ionization mass spectrometry.[Pubmed:10949478]

J Chromatogr A. 2000 Aug 4;888(1-2):113-20.

An analytical method for the determination of aldicarb, and its two major metabolites, aldicarb sulfoxide and Aldicarb sulfone in fruits and vegetables is described. Briefly the method consisted of the use of a methanolic extraction, liquid-liquid extraction followed by solid-phase extraction clean-up. Afterwards, the final extract is analyzed by liquid chromatography-atmospheric pressure chemical ionization mass spectrometry (LC-APCI-MS). The specific fragment ion corresponding to [M-74]+ and the protonated molecular [M+H]+ ion were used for the unequivocal determination of aldicarb and its two major metabolites. The analytical performance of the proposed method and the results achieved were compared with those obtained using the common analytical method involving LC with post-column fluorescence detection (FL). The limits of detection varied between 0.2 and 1.3 ng but under LC-FL were slightly lower than when using LC-APCI-MS. However both methods permitted one to achieve the desired sensitivity for analyzing aldicarb and its metabolites in vegetables. The method developed in this work was applied to the trace determination of aldicarb and its metabolites in crop and orange extracts.

Determination of aldicarb, aldicarb sulfoxide and aldicarb sulfone in tobacco using high-performance liquid chromatography with dual post-column reaction and fluorescence detection.[Pubmed:8199709]

J Chromatogr A. 1994 Apr 1;664(2):289-94.

A screening method for the determination of aldicarb (AS) and its sulfoxide (ASX) and sulfone (ASN) metabolites in tobacco at low ppm levels is described. Tobacco samples are extracted using methanol with the aid of sonication at ambient conditions. The extract is filtered and then injected into a high-performance liquid chromatograph equipped with a dual post-column reaction system and a fluorescence detector. Chromatographic separation is performed on a C18 column with a mixture of methanol-acetonitrile-water containing 0.1% of triethanolamine as the mobile phase. Triethanolamine is added to improve peak shape of AS residues and to reduce the undesired interaction between residual silanols and interferences, mainly amino acids and other amines. The average recoveries for AS residues spiked in tobacco are higher than 95% for AS, 91% for ASN and 85% for ASX at levels of 0.5-10 ppm (w/w). The detection limit is 0.5 ppm for each of the target compounds.

Description

Aldicarb sulfone(Temik sulfone) is a carbamate insecticide; is a cholinesterase inhibitor which prevents the breakdown of acetylcholine in the synapse.

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