BCC1290
(24S)-24,25-Dihydroxyvitamin D3
(24S)-24,25-Dihydroxycholecalciferol is an inactive form of vitamin D3 which undergoes various levels of hydroxylation to form active vitamin D3 analogs.
BCC3824
Nitazoxanide
Nitazoxanide is a synthetic nitrothiazolyl-salicylamide derivative and an antiprotozoal agent.
BCC1190
Acarbose
Acarbose is an inhibitor of alpha glucosidase, an anti-diabetic drug.
BCC4871
Torsemide
Torsemide is a pyridine-sulfonyl urea type loop diuretic.
BCC1193
Pamidronate Disodium
Pamidronate disodium, a bisphosphonate drug, can help to strengthen bones.
BCC1873
Puromycin aminonucleoside
Puromycin aminonucleoside (NSC 3056) is the aminonucleoside portion of the antibiotic puromycin, and used in nephrosis animal models. Puromycin aminonucleoside induces apoptosis. Puromycin aminonucleoside is a reversible inhibitor of dipeptidyl peptidase II and cytosol alanyl aminopeptidase.
BCN3841
Inosine
Inosine, an endogenous purine nucleoside, has immunomodulatory, neuroprotective, and analgesic properties.
BCC4786
Hydrochlorothiazide
Hydrochlorothiazide is a diuretic drug of the thiazide class.
BCC3752
Chlorothiazide
Chlorothiazide is a diuretic and antihypertensive. (IC50=3.8 mM)
BCC5210
Procaine
Procaine is a DNA-demethylating agent. Procaine acts through multiple targets and has a slow onset and a short duration of action.
BCC2545
Sulfasalazine
Sulfasalazine is a drug for the treatment of rheumatoid arthritis and ulcerative colitis. Sulfasalazine is reported to suppress NF-κB activity.
BCC4888
(6-)ε-Aminocaproic acid
6-Aminocaproic acid is an antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
BCC3812
Methimazole
Methimazole is an antithyroid medicine used for the treatment of the hyperthyroidism in humans and animals.
BCC1835
Pamabrom
Pamabron is a common over-the-counter diuretic used for relief of menstrual-associated symptoms.
BCC3804
Lithium Citrate
Citric acid trilithium salt tetrahydrate is a pharmaceutical and construction material, used in HPLC gradient elution for quantitative amino acid analysis.
BCC4283
L-Thyroxine sodium salt pentahydrate
L-Thyroxine sodium salt pentahydrate(Levothyroxine) is an iodine containing hormone produced from thyroglobulin in the thyroid follicular cells; reduces total cholesterol level, low-density lipoprotein cholesterol as well as waist to hip ratio in subclinical hypothyroidism pateints.
BCC3996
Vorapaxar
Vorapaxar (SCH 530348), an antiplatelet agent, is a selective, orally active, and competitive thrombin receptor protease-activated receptor (PAR-1) antagonist (Ki=8.1 nM). Vorapaxar (SCH 530348) inhibits thrombin receptor-activating peptide (TRAP)-induced platelet aggregation in a dose-dependent manner.
BCC5447
Oxiracetam
Oxiracetam is a cyclic derivative of γ-aminobutyric acid (GABA) which has been commonly used as nootropic drug to treat cognitive impairments.
BCC5477
NSC-41589
NSC-41589 is an N-[2-(methylsulfanyl) phenyl]acetamide.
BCC5472
Bromethalin
Bromethalin is a new rodenticide for the control of commensal rodents; doses in excess of the LD50 (2 mg/kg in rats) will cause death.
BCC5473
Cloxyfonac
Cloxyfonac is a plant growth regulator and a chemical transformation product; Pesticide agent.
BCC1562
Etimizol
Etimizol(Ethymisole; Antiffine; Ethylnorantifein) was shown to relieve amnesia effectively in the origin of which there is the hypoxic component (hypobaric hypoxia, actinomycin D, mechanical injury of the brain).
BCC5321
Tetrahydropapaverine HCl
Tetrahydropapaverine hydrochloride is one of the Tetrahydroisoquinolines. Tetrahydropapaverine hydrochloride has neurotoxic effects on dopamine neurons.
BCC2033
VcMMAE
VcMMAE (mc-vc-PAB-MMAE) is a drug-linker conjugate for ADC with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the lysosomally cleavable dipeptide, valine-citrulline (vc).
BCC5203
VGX-1027
VGX-1027(GIT27) is an isoxazole compound that exhibits various immunomodulatory properties; reduce the secretion of IL-1beta, TNF-alpha and IL-10 from purified murine macrophages.
BCC3769
Docosanol (Abreua)
1-Docosanol is a saturated fatty alcohol used traditionally as an emollient, emulsifier, and thickener in cosmetics, and nutritional supplement; inhibitor of lipid-enveloped viruses including herpes simplex.
BCC5328
Cyromazine
Cyromazine is a triazine insect growth regulator used as an insecticide and an acaricide.
BCC5324
Hypoxanthine
Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia.
BCC3744
Carbadox
Carbadox is a quinoxaline-di-N-oxide antibiotic compound which is widely fed to nursery-age pigs to control enteric diseases and improve feed efficiency.
BCC4169
(R)-Oxiracetam
(R)-Oxiracetam is the (R)-enantiomer of the nootropic drug oxiracetam. Oxiracetam (ISF 2522) is a nootropic drug of the racetam family and stimulant.
BCC4928
Pramiracetam
Pramiracetam is a nootropic drug derived from piracetam, and is more potent. Pramiracetam reportedly improved cognitive deficits associated with traumatic brain injuries.
BCC5318
Indole-3-carbinol
Indole-3-carbinol (I3C) inhibits NF-κB activity and also is an Aryl hydrocarbon receptor (AhR) agonist, and an inhibitor of WWP1 (WW domain-containing ubiquitin E3 ligase 1).
BCC7565
Pertussis Toxin
Pertussis Toxin is a protein-based AB5-type exotoxin produced by the bacterium Bordetella pertussis, which causes whooping cough.
BCC5342
FPH1 (BRD-6125)
FPH1 (BRD-6125) is a small molecule, which promotes expansion of iPS-derived hepatocytes.
BCC5187
Miglustat
Miglustat(OGT918) is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1).
BCN2196
Melatonin
Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Melatonin plays a role in sleep and possesses important antioxidative and anti-inflammatory properties. Melatonin is a novel selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation.
BCC5560
Hydroxychloroquine Sulfate
Hydroxychloroquine sulfate (HCQ sulfate) is a synthetic antimalarial drug which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling.
BCN4306
(-)-Usnic acid
(+)-Usnic acid is isolated from isolated from lichens, binds at the ATP-binding pocket of mTOR, and inhibits mTORC1/2 activity. (+)-Usnic acid inhibits the phosphorylation of mTOR downstream effectors: Akt (Ser473), 4EBP1, S6K, induces autophay, with anti-cancer activity.
BCC3871
Triamcinolone Acetonide
Triamcinolone acetonide is a more potent type of triamcinolone, being about 8 times as effective as prednisone.
BCC3809
Mepenzolate Bromide
Mepenzolate Bromide is a muscarinic antagonist used to treat gastrointestinal disorders, decreases the severity of elastase-induced airspace enlargement and respiratory dysfunction.
BCC5171
TPT-260
TPT-260(TPU260) is a thiophene thiourea derivative with molecule weight 260.00 in free base form; There is no formal name yet, we temporally call this molecule as TPT-260.
BCC4164
Gadobutrol
Gadobutrol (Gd-DO3A-butrol; ZK 135079) is a nonionic, paramagnetic contrast agent developed for tissue contrast enhancement in magnetic resonance imaging (MRI).
BCC1314
7-Epi 10-Desacetyl Paclitaxel
7-Epi 10-desacetyl paclitaxel (7-epi-10-deacetyltaxol), a taxol derivative, exhibits cytotoxicity against HeLa cells with an IC50 of 85 μM.
BCC2559
Cyclosporine
Cyclosporine is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation.
BCC3746
Casanthranol
Casanthranol is a concentrated mixture of anthranol glycosides from cascara sagrada (dried bark of Rhamnus p.) and used as a laxative in constipation and various medical conditions, stimulant laxative Casanthranol encourages bowel movements by acting on the intestinal wall to increase muscle contractions.
BCN5978
Stevenleaf
Gynostemma Extract (Ginsenoside C-Mx1) is a natural product.
BCC5320
Sapogenins Glycosides
Saponins are a class of chemical compounds of glycosides found in particular abundance in various plant species. In plants, saponins may serve as anti-feedants, and to protect the plant against microbes and fungi.
BCC4362
Phenformin HCl
Phenformin hydrochloride is an anti-diabetic drug from the biguanide class, can activate AMPK activity.
BCC2080
A-769662
A-769662 is a potent, reversible AMPK activator with EC50 of 0.8 μM.
BCC5317
Grape Seed Extract
Grape seed extract is a natural product with various health benefits, including anti-inflammatory effect. Grape seed extract shows inhibitory activity on the fat-metabolizing enzymes pancreatic lipase and lipoprotein lipase.
BCC5019
Benazepril HCl
Benazepril hydrochloride, an angiotensin converting enzyme inhibitor, which is a medication used to treat high blood pressure.
BCC4286
Benazepril
Benazepril, an angiotensin converting enzyme inhibitor, which is a medication used to treat high blood pressure.
BCC5375
Neuropathiazol
Neuropathiazol is a synthetic small molecule that induces neuronal differentiation of adult hippocampal neural progenitor cells.
BCN2457
Artesunate
Artesunate is a part of the artemisinin group of agents with an IC50 of < 5 μM for small cell lung carcinoma cell line H69. It is a potential inhibitor of STAT-3 and exhibits selective cytotoxicity of cancer cells over normal cells in vitro; A potent inhibitor of EXP1.
BCC2480
Edaravone
Edaravone is a strong novel free radical scavenger, and inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator.
BCC5428
BAMB-4
BAMB-4(ITPKA-IN-C14) is a new membrane-permeable inhibitor against inositol-1,4,5-trisphosphate-3-kinase A((ITPKA) with IC50 of 37 μM in ADP-Glo Assay.
BCC1171
SC 144
SC144 is the first-in-class orally active small-molecule gp130 inhibitor; inhibits cell growth in a panel of human ovarian cancer cell lines with IC50 values in a submicromolar range.
BCN2563
4-Methylumbelliferone
4-Methylumbelliferone is a hyaluronic acid biosynthesis inhibitor with antitumoral and antimetastatic effects.
BCC6493
Xanthone
Xanthone is isolated from Mangosteen and is known to control cell division and growth, apoptosis, inflammation, and metastasis in different stages of carcinogenesis. Xanthone has anti-oxidant, anti-tumor, anti-allergic, anti-inflammatory, anti-bacterial, anti-fungal, and anti-viral activities.
BCC6451
PF-3274167
Cligosiban (PF-3274167), a high oral bioavailability and good brain-penetrant non-peptide oxytocin receptor antagonist, shows a high-affinity (Ki=9.5 nM) and an excellent selectivity versus the vasopressin receptors with almost no affinity for the V1b and V1a subtypes. Cligosiban inhibits ejaculatory physiology in rodents.
BCC4367
TAME
TAME is an inhibitor of anaphase-promoting complex/cyclosome (APC/C or APC), which binds to APC/C and prevents its activation by Cdc20 and Cdh1, produces mitotic arrest.
BCN2947
10-Deacetyl-7-xylosyl paclitaxel
10-Deacetyl-7-xylosyl paclitaxel is a Paclitaxel (a microtubule stabilizing agent; enhances tubulin polymerization) derivative with improved pharmacological features.
BCC4285
Adapalene sodium salt
Adapalene sodium salt(CD 271; Differin), a synthetic retinoid, is a Retinoic acid receptor agonist (RAR).
BCC3819
Noscapine HCl
Bradykinin antagonist. Also tubulin inhibitor
BCC4163
GSK962040
Camicinal (GSK962040) is a small molecule, selective motilin receptor agonist with pEC50 of 7.9.
BCC5617
T 5601640
T56-LIMKi is a selective inhibitor of LIMK2; inhibits the growth of Panc-1 cells with an IC50 of 35.2 μM.
BCN2977
Guaifenesin
Guaifenesin is an expectorant that also has some muscle relaxing action.
BCC5378
TH-237A
TH-237A(meso-GS 164) is a novel neuroprotective agent exhibiting favorable permeation across the blood brain barrier.
BCC3855
Sodium 4-amiropparaty Hyalrate
Aminohippurate sodium is a diagnostic agent useful in medical tests involving the kidney used in the measurement of renal plasma flow.
BCC3847
Ranolazine
Ranolazine (CVT 303) is an anti-angina drug that achieves its effects by inhibiting the late phase of inward sodium current (INa and IKr with IC50 values of 6 μM and 12 μM, respectively) without affecting heart rate or blood pressure (BP). Ranolazine is also a partial fatty acid oxidation (FAO) inhibitor.
BCC2488
BTZ043 Racemate
BTZ043 Racemate is the racemate of BTZ043. BTZ043 is an inhibitor of decaprenyl-phosphoribose-epimerase (DprE1), and the antimicrobial activity of BTZ043 is more potent than BTZ043 Racemate.
BCC5451
FPH2 (BRD-9424)
FPH2 induces of functional proliferation of primary human hepatocytes and may lead to the development of new therapeutics for liver diseases.
BCC5433
2'-Deoxyguanosine
2'-Deoxyguanosine (Deoxyguanosine) is composed of the purine nucleoside guanine linked by its N9 nitrogen to the C1 carbon of deoxyribose.
BCC3830
Orlistat
Orlistat is a lipase inhibitor for obesity management that acts by inhibiting the absorption of dietary fats.
BCC7886
BTZO 1
BTZO-1 binds to Macrophage migration inhibitory factor (MIF) with a Kd value of 68.6 nM, and its binding requires the N-terminal Pro1. BTZO-1 can activate antioxidant response element (ARE)-mediated gene expression and suppress oxidative stress-induced cardiomyocyte apoptosis in vitro.
