Home >> Research Area >>Others>>Others>> Difloxacin HCl

Difloxacin HCl

quinolone antimicrobial antibiotic CAS# 98106-17-3

Difloxacin HCl

Catalog No. BCC3764----Order now to get a substantial discount!

Product Name & Size Price Stock
Difloxacin HCl: 5mg $6 In Stock
Difloxacin HCl: 10mg Please Inquire In Stock
Difloxacin HCl: 20mg Please Inquire Please Inquire
Difloxacin HCl: 50mg Please Inquire Please Inquire
Difloxacin HCl: 100mg Please Inquire Please Inquire
Difloxacin HCl: 200mg Please Inquire Please Inquire
Difloxacin HCl: 500mg Please Inquire Please Inquire
Difloxacin HCl: 1000mg Please Inquire Please Inquire
Related Products

Quality Control of Difloxacin HCl

Number of papers citing our products

Chemical structure

Difloxacin HCl

3D structure

Chemical Properties of Difloxacin HCl

Cas No. 98106-17-3 SDF Download SDF
PubChem ID 56206 Appearance Powder
Formula C21H19F2N3O3 HCl M.Wt 435.86
Type of Compound N/A Storage Desiccate at -20°C
Solubility Soluble in DMSO
Chemical Name 6-fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
SMILES CN1CCN(CC1)C2=C(C=C3C(=C2)N(C=C(C3=O)C(=O)O)C4=CC=C(C=C4)F)F
Standard InChIKey NOCJXYPHIIZEHN-UHFFFAOYSA-N
Standard InChI InChI=1S/C21H19F2N3O3/c1-24-6-8-25(9-7-24)19-11-18-15(10-17(19)23)20(27)16(21(28)29)12-26(18)14-4-2-13(22)3-5-14/h2-5,10-12H,6-9H2,1H3,(H,28,29)
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Difloxacin HCl Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

Difloxacin HCl Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of Difloxacin HCl

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.2943 mL 11.4716 mL 22.9431 mL 45.8863 mL 57.3579 mL
5 mM 0.4589 mL 2.2943 mL 4.5886 mL 9.1773 mL 11.4716 mL
10 mM 0.2294 mL 1.1472 mL 2.2943 mL 4.5886 mL 5.7358 mL
50 mM 0.0459 mL 0.2294 mL 0.4589 mL 0.9177 mL 1.1472 mL
100 mM 0.0229 mL 0.1147 mL 0.2294 mL 0.4589 mL 0.5736 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University

Background on Difloxacin HCl

Difloxacin HCl is a quinolone antimicrobial antibiotic [1].
Quinolone antibiotics target bacterial DNA gyrase which is required during DNA replication, subsequent DNA synthesis and ultimately cell division.
In unselected cultured human neuroblastoma cells, difloxacin (50 microg/ml) increased sensitivity to the multidrug resistance-associated protein (MRP) substrates. Daunorubicin, doxorubicin, vincristine and potassium antimony tartrate is proportional to the level of MRP expression, which proves that difloxacin HCl reverse drug resistance in human neuroblastoma cells [1].
Difloxacin HCl is a quinolone antimicrobial antibiotic and may reverse drug resistance in human neuroblastoma cells. Difloxacin HCl is commonly used in clinical in vitro antimicrobial susceptibility tests against gram-positive and gram-negative microbial isolates. Medical microbiologists use AST results to recommend antibiotic treatment options for infected patients.
References:
[1]. Norris MD, Madafiglio J, Gilbert J, et al. Reversal of multidrug resistance-associated protein-mediated drug resistance in cultured human neuroblastoma cells by the quinolone antibiotic difloxacin. Med Pediatr Oncol, 2001, 36(1): 177-180.

Featured Products
New Products
 

Keywords:

Difloxacin HCl,98106-17-3,Natural Products,Others, buy Difloxacin HCl , Difloxacin HCl supplier , purchase Difloxacin HCl , Difloxacin HCl cost , Difloxacin HCl manufacturer , order Difloxacin HCl , high purity Difloxacin HCl

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: