Rhombifoline

CAS# 529-78-2

Rhombifoline

2D Structure

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Quality Control of Rhombifoline

3D structure

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Rhombifoline

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Chemical Properties of Rhombifoline

Cas No. 529-78-2 SDF Download SDF
PubChem ID 92795 Appearance Oil
Formula C15H20N2O M.Wt 244.34
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (1~{R},9~{S})-11-but-3-enyl-7,11-diazatricyclo[7.3.1.0^{2,7}]trideca-2,4-dien-6-one
SMILES C=CCCN1CC2CC(C1)C3=CC=CC(=O)N3C2
Standard InChIKey ZVTFRRVBMAUIQW-QWHCGFSZSA-N
Standard InChI InChI=1S/C15H20N2O/c1-2-3-7-16-9-12-8-13(11-16)14-5-4-6-15(18)17(14)10-12/h2,4-6,12-13H,1,3,7-11H2/t12-,13+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Rhombifoline

The herbs of Thermopsis chinensis Benth.

Biological Activity of Rhombifoline

In vitro

Chemotaxonomy of Portuguese Ulex: quinolizidine alkaloids as taxonomical markers.[Pubmed: 16876210 ]

Phytochemistry. 2006 Sep;67(17):1943-9. Epub 2006 Jul 28.

Six species of Portuguese Ulex L. in a total of nineteen populations were studied by GC-EIMS as to their content in quinolizidine alkaloids.
METHODS AND RESULTS:
Sparteine, beta-isosparteine, jussiaeiine A, N-methylcytisine, cytisine, 5,6-dehydrolupanine, Rhombifoline, lupanine, jussiaeiine B, N-formylcytisine, N-acetylcytisine, anagyrine, jussiaeiine C, jussiaeiine D, pohakuline, baptifoline, and epibaptifoline were detected. Analysis of the chromatograms showed that the chemical profile of all species was mainly composed of N-methylcytisine, cytisine, anagyrine, and jussiaeiines A, B, C and D. Therefore a quantification study of these alkaloids in all the populations studied was done by GC.
CONCLUSIONS:
These data were then submitted to cluster analysis and principal component analysis, which allowed the definition of five chemotypes and the recognition of hybrids. N-methylcytisine, cytisine, and jussiaeiines A, C and D are recognized as markers of this genus in Portugal.

Protocol of Rhombifoline

Structure Identification
Arch Pharm Res. 1994 Dec;17(6):393-7.

Rhombifoline and 5,6-dehydrolupanine from Anagyrus foetida L.[Pubmed: 10319146 ]


METHODS AND RESULTS:
Rhombifoline and 5,6-dehydrolupanine were isolated for the first time from the leaves and stems of A. foetida L. indigenous to Saudi Arabia. In addition, five other alkaloids, previously identified in A. foetidia L., namely N-methylcytisine, sparteine, anagyrine, lupanine and cytisine, were isolated. The isolated alkaloids were characterized by UV, 1H-NMR, 13C-NMR and Mass spectral data.
CONCLUSIONS:
13C-NMR data of Rhombifoline and 5,6-dehydrolupanine are reported for the first time.

Rhombifoline Dilution Calculator

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Rhombifoline Molarity Calculator

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Preparing Stock Solutions of Rhombifoline

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.0927 mL 20.4633 mL 40.9266 mL 81.8532 mL 102.3164 mL
5 mM 0.8185 mL 4.0927 mL 8.1853 mL 16.3706 mL 20.4633 mL
10 mM 0.4093 mL 2.0463 mL 4.0927 mL 8.1853 mL 10.2316 mL
50 mM 0.0819 mL 0.4093 mL 0.8185 mL 1.6371 mL 2.0463 mL
100 mM 0.0409 mL 0.2046 mL 0.4093 mL 0.8185 mL 1.0232 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Rhombifoline

Rhombifoline and 5,6-dehydrolupanine from Anagyrus foetida L.[Pubmed:10319146]

Arch Pharm Res. 1994 Dec;17(6):393-7.

Rhombifoline and 5,6-dehydrolupanine were isolated for the first time from the leaves and stems of A. foetida L. indigenous to Saudi Arabia. In addition, five other alkaloids, previously identified in A. foetidia L., namely N-methylcytisine, sparteine, anagyrine, lupanine and cytisine, were isolated. The isolated alkaloids were characterized by UV, 1H-NMR, 13C-NMR and Mass spectral data. 13C-NMR data of Rhombifoline and 5,6-dehydrolupanine are reported for the first time.

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