(S)-(-)-beta-CitronellolCAS# 7540-51-4 |
Quality Control & MSDS
Package In Stock
Number of papers citing our products
| Cas No. | 7540-51-4 | SDF | Download SDF |
| PubChem ID | N/A | Appearance | Oil |
| Formula | C10H20O | M.Wt | 156.2 |
| Type of Compound | Monoterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | (S)-(-)-beta-Citronellol may inhibit P-gp-mediated transport and interact with P-gp substrates in the intestinal absorption process. | |||||
(S)-(-)-beta-Citronellol Dilution Calculator
(S)-(-)-beta-Citronellol Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 6.402 mL | 32.0102 mL | 64.0205 mL | 128.041 mL | 160.0512 mL |
| 5 mM | 1.2804 mL | 6.402 mL | 12.8041 mL | 25.6082 mL | 32.0102 mL |
| 10 mM | 0.6402 mL | 3.201 mL | 6.402 mL | 12.8041 mL | 16.0051 mL |
| 50 mM | 0.128 mL | 0.6402 mL | 1.2804 mL | 2.5608 mL | 3.201 mL |
| 100 mM | 0.064 mL | 0.3201 mL | 0.6402 mL | 1.2804 mL | 1.6005 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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(R)-(+)-beta-Citronellol and (S)-(-)-beta-Citronellol in Combination with Amphotericin B against Candida Spp.[Pubmed:32150884]
Int J Mol Sci. 2020 Mar 5;21(5). pii: ijms21051785.
The enantiomers (R)-(+)-beta-citronellol and (S)-(-)-beta-Citronellol are present in many medicinal plants, but little is understood about their bioactivity against Candida yeasts. This study aimed to evaluate the behavior of positive and negative enantiomers of beta-citronellol on strains of Candida albicans and C. tropicalis involved in candidemia. The minimum inhibitory concentration (MIC) and minimum fungicide concentration (MFC) were determined. The evaluation of growth kinetics, mechanism of action, and association studies with Amphotericin B (AB) using the checkerboard method was also performed. R-(+)-beta-citronellol and S-(-)-beta-citronellol presented a MIC50% of 64 microg/mL and a MFC50% of 256 microg/mL for C. albicans strains. For C. tropicalis, the isomers exhibited a MIC50% of 256 microg/mL and a MFC50% of 1024 microg/mL. In the mechanism of action assay, both substances displayed an effect on the fungal membrane but not on the fungal cell wall. Synergism and indifference were observed in the association of R-(+)-beta-citronellol and AB, while the association between S-(-)-beta-citronellol and AB displayed synergism, additivity, and indifference. In conclusion, both isomers of beta-citronellol presented a similar profile of antifungal activity. Hence, they can be contemplated in the development of new antifungal drugs providing that further research is conducted about their pharmacology and toxicity.
