SRT3190CXCR2 ligand,SIRT1 activator CAS# 1204707-73-2 |
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Quality Control & MSDS
3D structure
Package In Stock
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| Cas No. | 1204707-73-2 | SDF | Download SDF |
| PubChem ID | 59149652 | Appearance | Powder |
| Formula | C18H23F2N5O4S2 | M.Wt | 475.54 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Solubility | DMSO : ≥ 100 mg/mL (210.29 mM) *"≥" means soluble, but saturation unknown. | ||
| Chemical Name | N-[2-[(2,3-difluorophenyl)methylsulfanyl]-6-[[(2S,3R)-3,4-dihydroxybutan-2-yl]amino]pyrimidin-4-yl]azetidine-1-sulfonamide | ||
| SMILES | CC(C(CO)O)NC1=CC(=NC(=N1)SCC2=C(C(=CC=C2)F)F)NS(=O)(=O)N3CCC3 | ||
| Standard InChIKey | QVKPEMXUBULFBM-FZMZJTMJSA-N | ||
| Standard InChI | InChI=1S/C18H23F2N5O4S2/c1-11(14(27)9-26)21-15-8-16(24-31(28,29)25-6-3-7-25)23-18(22-15)30-10-12-4-2-5-13(19)17(12)20/h2,4-5,8,11,14,26-27H,3,6-7,9-10H2,1H3,(H2,21,22,23,24)/t11-,14-/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | SRT3190 is CXCR2 ligand. |
SRT3190 Dilution Calculator
SRT3190 Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.1029 mL | 10.5144 mL | 21.0287 mL | 42.0575 mL | 52.5718 mL |
| 5 mM | 0.4206 mL | 2.1029 mL | 4.2057 mL | 8.4115 mL | 10.5144 mL |
| 10 mM | 0.2103 mL | 1.0514 mL | 2.1029 mL | 4.2057 mL | 5.2572 mL |
| 50 mM | 0.0421 mL | 0.2103 mL | 0.4206 mL | 0.8411 mL | 1.0514 mL |
| 100 mM | 0.021 mL | 0.1051 mL | 0.2103 mL | 0.4206 mL | 0.5257 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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SRT1720 is a selective SIRT1 activator with EC50 of 0.16 μM, but is >230-fold less potent for SIRT2 and SIRT3.
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SRT3190 is an antagonist of CXCR2, used in the research of chemokine mediated diseases.
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