SRT3109

CAS# 1204707-71-0

SRT3109

Catalog No. BCC1965----Order now to get a substantial discount!

Product Name & Size Price Stock
SRT3109: 5mg $322 In Stock
SRT3109: 10mg Please Inquire In Stock
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Chemical structure

SRT3109

3D structure

Chemical Properties of SRT3109

Cas No. 1204707-71-0 SDF Download SDF
PubChem ID 44602493 Appearance Powder
Formula C18H23F2N5O4S2 M.Wt 475.53
Type of Compound N/A Storage Desiccate at -20°C
Solubility DMSO : ≥ 100 mg/mL (210.29 mM)
*"≥" means soluble, but saturation unknown.
Chemical Name N-[2-[(2,3-difluorophenyl)methylsulfanyl]-6-[[(2R,3R)-3,4-dihydroxybutan-2-yl]amino]pyrimidin-4-yl]azetidine-1-sulfonamide
SMILES CC(C(CO)O)NC1=CC(=NC(=N1)SCC2=C(C(=CC=C2)F)F)NS(=O)(=O)N3CCC3
Standard InChIKey QVKPEMXUBULFBM-RISCZKNCSA-N
Standard InChI InChI=1S/C18H23F2N5O4S2/c1-11(14(27)9-26)21-15-8-16(24-31(28,29)25-6-3-7-25)23-18(22-15)30-10-12-4-2-5-13(19)17(12)20/h2,4-5,8,11,14,26-27H,3,6-7,9-10H2,1H3,(H2,21,22,23,24)/t11-,14+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Biological Activity of SRT3109

DescriptionSRT3109 is a CXCR2 ligand for use in the treatment of chemokine mediated diseases and conditions.

SRT3109 Dilution Calculator

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SRT3109 Molarity Calculator

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Preparing Stock Solutions of SRT3109

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.1029 mL 10.5146 mL 21.0292 mL 42.0583 mL 52.5729 mL
5 mM 0.4206 mL 2.1029 mL 4.2058 mL 8.4117 mL 10.5146 mL
10 mM 0.2103 mL 1.0515 mL 2.1029 mL 4.2058 mL 5.2573 mL
50 mM 0.0421 mL 0.2103 mL 0.4206 mL 0.8412 mL 1.0515 mL
100 mM 0.021 mL 0.1051 mL 0.2103 mL 0.4206 mL 0.5257 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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Background on SRT3109

SRT3109 is a CXCR2 ligand for use in the treatment of chemokine mediated diseases and conditions.

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Description

SRT3109 is an antagonist of CXCR2, with a pIC50 of 8.2, and used in the research of chemokine mediated diseases.

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