Sarracenin

CAS# 59653-37-1

Sarracenin

Catalog No. BCN8586----Order now to get a substantial discount!

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Quality Control of Sarracenin

Number of papers citing our products

Chemical structure

Sarracenin

3D structure

Chemical Properties of Sarracenin

Cas No. 59653-37-1 SDF Download SDF
PubChem ID 427877 Appearance Powder
Formula C11H14O5 M.Wt 226.22
Type of Compound Iridoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name methyl 9-methyl-2,4,10-trioxatricyclo[5.3.1.03,8]undec-5-ene-6-carboxylate
SMILES CC1C2C3CC(O1)OC2OC=C3C(=O)OC
Standard InChIKey QGBCGMGBGAHJIT-UHFFFAOYSA-N
Standard InChI InChI=1S/C11H14O5/c1-5-9-6-3-8(15-5)16-11(9)14-4-7(6)10(12)13-2/h4-6,8-9,11H,3H2,1-2H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Sarracenin

The herbs of Lonicera morrowii

Biological Activity of Sarracenin

In vitro

Iridoid Glucosides from Chinese Herb Lonicera chrysatha and Their Antitumor Activity.[Reference: WebLink]

Journal of Chemical Research,2003(10):676-677.


METHODS AND RESULTS:
A new bis-iridoid glucosides, secologanin methyl hemiacetal-yl-6`- secologanin dimethyl acetal (chrysathain, 1), was isolated from the methanol extract of the leaves of Chinese medicinal plant Lonicera chrysatha along with nine known iridoid glucosides, i.e., loganin (2), secologanin (3), secologanin dimethylacetal (4), 8-epi-kingiside (5) 7α-morroniside (6), 7β-morroniside (7), vogeloside (8) 7-epi-vogeloside (9) and Sarracenin (10). Their structures were elucidated by spectroscopic methods.
CONCLUSIONS:
Compounds 1-5 showed moderate in vitro antitumour activity against human promyelocytic leukemia (HL-60) cells.

Protocol of Sarracenin

Structure Identification
Nat Prod Res. 2011 Oct;25(17):1614-20.

A new iridoid from Guettarda grazielae M.R.V. Barbosa (Rubiaceae).[Pubmed: 22011220 ]


METHODS AND RESULTS:
Chromatographic fractionation of the chloroform extracts from the stem bark and stems of Guettarda grazielae resulted in the isolation of a new iridoid (guettardodiol, 1) and the secoiridoid Sarracenin (2), described for the first time in this genus.
CONCLUSIONS:
The structural elucidation of these compounds was based on spectroscopic analyses (IR, MS as well as 1-D and 2-D NMR experiments).

Sarracenin Dilution Calculator

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Sarracenin Molarity Calculator

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Preparing Stock Solutions of Sarracenin

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.4205 mL 22.1024 mL 44.2048 mL 88.4095 mL 110.5119 mL
5 mM 0.8841 mL 4.4205 mL 8.841 mL 17.6819 mL 22.1024 mL
10 mM 0.442 mL 2.2102 mL 4.4205 mL 8.841 mL 11.0512 mL
50 mM 0.0884 mL 0.442 mL 0.8841 mL 1.7682 mL 2.2102 mL
100 mM 0.0442 mL 0.221 mL 0.442 mL 0.8841 mL 1.1051 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Sarracenin

A new iridoid from Guettarda grazielae M.R.V. Barbosa (Rubiaceae).[Pubmed:22011220]

Nat Prod Res. 2011 Oct;25(17):1614-20.

Chromatographic fractionation of the chloroform extracts from the stem bark and stems of Guettarda grazielae resulted in the isolation of a new iridoid (guettardodiol, 1) and the secoiridoid Sarracenin (2), described for the first time in this genus. The structural elucidation of these compounds was based on spectroscopic analyses (IR, MS as well as 1-D and 2-D NMR experiments).

Description

Sarracenin is a iridoid isolated from roots and rhizomes of Patrinia heterophylla. Sarracenin shows cytotoxic activities against tumor cells.

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