CinobufaginolCAS# 6691-83-4 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
Cas No. | 6691-83-4 | SDF | Download SDF |
PubChem ID | 12303266 | Appearance | Powder |
Formula | C26H34O7 | M.Wt | 458.55 |
Type of Compound | Steroids | Storage | Desiccate at -20°C |
Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
SMILES | CC(=O)OC1C(C2(CCC3C(C24C1O4)CCC5C3(CCC(C5)O)CO)C)C6=COC(=O)C=C6 | ||
Standard InChIKey | KDRVIPFIZZDLGB-CDIOGTMDSA-N | ||
Standard InChI | InChI=1S/C26H34O7/c1-14(28)32-22-21(15-3-6-20(30)31-12-15)24(2)9-8-18-19(26(24)23(22)33-26)5-4-16-11-17(29)7-10-25(16,18)13-27/h3,6,12,16-19,21-23,27,29H,4-5,7-11,13H2,1-2H3/t16-,17+,18+,19-,21+,22-,23-,24-,25-,26-/m1/s1 | ||
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. |
Structure Identification | Chemical Research in Chinese Universities, 2009, 25(6):801-806.Simultaneous Determination of Bufadienolides and Qualitative Evaluation for Venenum Bufonis by High Performance Liquid Chromatography[Reference: WebLink]
A high performance liquid chromatographic method was used for the simultaneous identification and qua-litative evaluation of 12 bufadienolides(resibufogenin, cinobufagin, Cinobufaginol, arenobufagin, bufalin, bufotalin, gamabufotalin, cinobufotalin, Ψ-bufaranogin, desacetylcinobufagin, telocinobufagin and resibufogenol) in Venenum Bufonis.
|
Cinobufaginol Dilution Calculator
Cinobufaginol Molarity Calculator
1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
1 mM | 2.1808 mL | 10.9039 mL | 21.8079 mL | 43.6157 mL | 54.5197 mL |
5 mM | 0.4362 mL | 2.1808 mL | 4.3616 mL | 8.7231 mL | 10.9039 mL |
10 mM | 0.2181 mL | 1.0904 mL | 2.1808 mL | 4.3616 mL | 5.452 mL |
50 mM | 0.0436 mL | 0.2181 mL | 0.4362 mL | 0.8723 mL | 1.0904 mL |
100 mM | 0.0218 mL | 0.109 mL | 0.2181 mL | 0.4362 mL | 0.5452 mL |
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. |
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- Licoflavone B
Catalog No.:BCN8592
CAS No.:91433-17-9
- Firmanoic acid
Catalog No.:BCN8591
CAS No.:107584-83-8
- Aaptamine
Catalog No.:BCN8590
CAS No.:85547-22-4
- Hydroquinidine
Catalog No.:BCN8589
CAS No.:1435-55-8
- Rubiayannone A
Catalog No.:BCN8588
CAS No.:517978-25-1
- Glyasperin C
Catalog No.:BCN8587
CAS No.:142474-53-1
- Sarracenin
Catalog No.:BCN8586
CAS No.:59653-37-1
- Platycodin D3
Catalog No.:BCN8585
CAS No.:67884-03-1
- Lucidin 3-O-primeveroside
Catalog No.:BCN8584
CAS No.:29706-59-0
- Ligupurpuroside C
Catalog No.:BCN8583
CAS No.:1194056-33-1
- Isorosmanol
Catalog No.:BCN8582
CAS No.:93780-80-4
- Isoginsenoside Rh3
Catalog No.:BCN8581
CAS No.:166040-90-0
- Jasminoside B
Catalog No.:BCN8594
CAS No.:214125-04-9
- Ophiopogonoside A
Catalog No.:BCN8595
CAS No.:791849-22-4
- Dehydronuciferine
Catalog No.:BCN8596
CAS No.:7630-74-2
- Licoflavone A
Catalog No.:BCN8597
CAS No.:61153-77-3
- Eriosematin
Catalog No.:BCN8598
CAS No.:168010-17-1
- Isoastragaloside IV
Catalog No.:BCN8599
CAS No.:136033-55-1
- Astraganoside
Catalog No.:BCN8600
CAS No.:1011711-05-9
- Rubipodanone A
Catalog No.:BCN8601
CAS No.:2170211-22-8
- Asperosaponin IV
Catalog No.:BCN8602
CAS No.:126778-93-6
- 9-Methymyrrhone
Catalog No.:BCN8603
CAS No.:1809980-22-0
- Uvarigranol C
Catalog No.:BCN8604
CAS No.:172104-04-0
- Saikosaponin I
Catalog No.:BCN8605
CAS No.:103629-71-6
Simultaneous Determination of Bufadienolides and Qualitative Evaluation for Venenum Bufonis by High Performance Liquid Chromatography
Chemical Research in Chinese Universities, 2009, 25(6):801-806.
A high performance liquid chromatographic method was used for the simultaneous identification and qua-litative evaluation of 12 bufadienolides(resibufogenin, cinobufagin, Cinobufaginol, arenobufagin, bufalin, bufotalin, gamabufotalin, cinobufotalin, Ψ-bufaranogin, desacetylcinobufagin, telocinobufagin and resibufogenol) in Venenum Bufonis. The chromatographic separation was performed on a Dikma C 18 analytical column via gradient elution with an aqueous solution of acetonitrile and 0.3% acetic acid at a flow rate of 0.8 mL/min. The method was validated to be acceptable in consideration of linearity(r 2 > 0.9992) and recovery(ranged from 98.9% to 102.0%). The limits of de-tection of the bufadienolides were from 0.48 ng for bufalin to 6.00 ng for cinobufotalin. The intra-day and inter-day precisions of the method were evaluated and were less than 3.0%. The method was successfully used to analyze 19 batches of Venenum Bufonis, and the similarity values between batches were calculated by Similarity Evaluation System for Chromatographic Fingerprint of TCM(Version 2004A, Chinese Pharmacopoeia Committee, Beijing). The results show that the contents of bufadienolides in the medicine and the similarity values based on these bufadieno-lides varied significantly from batch to batch. This proposed method could be utilized to qualify and control Venenum Bufonis to ensure its safety and efficacy in application.