Sugeroside

CAS# 41743-57-1

Sugeroside

Catalog No. BCN6961----Order now to get a substantial discount!

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Sugeroside: 5mg $903 In Stock
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Quality Control of Sugeroside

Number of papers citing our products

Chemical structure

Sugeroside

3D structure

Chemical Properties of Sugeroside

Cas No. 41743-57-1 SDF Download SDF
PubChem ID 3082543 Appearance Powder
Formula C26H42O8 M.Wt 482.61
Type of Compound Diterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CC1(C2CCC34CC(CCC3C2(CCC1=O)C)C(C4)(COC5C(C(C(C(O5)CO)O)O)O)O)C
Standard InChIKey XOCBTSXQUYSHOW-UHFFFAOYSA-N
Standard InChI InChI=1S/C26H42O8/c1-23(2)16-6-9-25-10-14(4-5-17(25)24(16,3)8-7-18(23)28)26(32,12-25)13-33-22-21(31)20(30)19(29)15(11-27)34-22/h14-17,19-22,27,29-32H,4-13H2,1-3H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Sugeroside

The flower heads of Achillea clypeolata.

Biological Activity of Sugeroside

DescriptionSugeroside is a natural product from Achillea clypeolata.

Protocol of Sugeroside

Structure Identification
Zeitschrift Für Naturforschung B, 2007, 38(25):267-271.

Sesquiterpenes and Phenolic Compounds from Achillea clypeolata.[Reference: WebLink]


METHODS AND RESULTS:
The investigation of a dichloromethane extract of flower heads of Achillea clypeolata collected in Bulgaria led to the isolation of one guaiane (4,10,11-trihydroxy-guaiane, 1), four eudesmanes (4(15)-eudesmene-1β ,11-diol, 2, clypeotriol, 3, 3-epi-clypeotriol, 4, cryptomeridiol, 5), one diterpene (Sugeroside, 6) and two phenolic compounds (centaureidin, 7 and scopoletin, 8).
CONCLUSIONS:
Their structures were elucidated by UV/vis, EI- and CI-MS as well as by one- and two-dimensional NMR experiments. 4,10,11-Trihydroxy-guaiane (1) and 3-epi-clypeotriol (4) are reported here for the first time.

Sugeroside Dilution Calculator

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Sugeroside Molarity Calculator

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Preparing Stock Solutions of Sugeroside

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.0721 mL 10.3603 mL 20.7207 mL 41.4413 mL 51.8017 mL
5 mM 0.4144 mL 2.0721 mL 4.1441 mL 8.2883 mL 10.3603 mL
10 mM 0.2072 mL 1.036 mL 2.0721 mL 4.1441 mL 5.1802 mL
50 mM 0.0414 mL 0.2072 mL 0.4144 mL 0.8288 mL 1.036 mL
100 mM 0.0207 mL 0.1036 mL 0.2072 mL 0.4144 mL 0.518 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Sugeroside

Eight ent-Kaurane Diterpenoid Glycosides Named Diosmariosides A-H from the Leaves of Diospyros maritima and Their Cytotoxic Activity.[Pubmed:30381658]

Chem Pharm Bull (Tokyo). 2018;66(11):1057-1064.

From the leaves of Diospyros maritima, collected from Okinawa Island, eight new glycosides based on ent-kaurane-type diterpenoids, entitled diosmariosides A-H, were isolated. The absolute structure of diosmarioside E (5) was determined by X-ray crystallographic analysis. The structure of diosmarioside H was elucidated to be a dimeric compound between diosmarioside A and a Sugeroside through a ketal bond. An assay of cytotoxicity towards the lung adenocarcinoma (A549) cell line was performed. Among the compounds isolated, only diosmarioside D (4) and Sugeroside 9 showed strong activity. The anti-microbial activity toward multi-drug resistant strains was also determined, but no activity was observed.

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