Taxezopidine LCAS# 219749-76-5 |
Quality Control & MSDS
3D structure
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| Cas No. | 219749-76-5 | SDF | Download SDF |
| PubChem ID | 10078812 | Appearance | Powder |
| Formula | C39H46O15 | M.Wt | 754.78 |
| Type of Compound | Diterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| SMILES | CC(=O)OCC12C(CC(C(=C)C1C(C3CC(=O)C4(C(C3(CO4)C)(C(C2OC(=O)C)OC(=O)C)O)C)OC(=O)C)OC(=O)C=CC5=CC=CC=C5)OC(=O)C | ||
| Standard InChIKey | YJLKXWCZWJGUAN-OILLXYFHSA-N | ||
| Standard InChI | InChI=1S/C39H46O15/c1-20-28(54-31(46)15-14-26-12-10-9-11-13-26)17-30(50-22(3)41)38(19-48-21(2)40)32(20)33(51-23(4)42)27-16-29(45)37(8)39(47,36(27,7)18-49-37)35(53-25(6)44)34(38)52-24(5)43/h9-15,27-28,30,32-35,47H,1,16-19H2,2-8H3/b15-14+/t27-,28-,30-,32-,33+,34-,35-,36-,37+,38+,39-/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The seeds of the Japanese yew Taxus cuspidata Sieb. et Zucc.
| Description | 1. Taxezopidines K and taxezopidine L can markedly inhibit Ca2+-induced depolymerization of microtubules. |
| Targets | Calcium Channel |
Taxezopidine L Dilution Calculator
Taxezopidine L Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.3249 mL | 6.6244 mL | 13.2489 mL | 26.4978 mL | 33.1222 mL |
| 5 mM | 0.265 mL | 1.3249 mL | 2.6498 mL | 5.2996 mL | 6.6244 mL |
| 10 mM | 0.1325 mL | 0.6624 mL | 1.3249 mL | 2.6498 mL | 3.3122 mL |
| 50 mM | 0.0265 mL | 0.1325 mL | 0.265 mL | 0.53 mL | 0.6624 mL |
| 100 mM | 0.0132 mL | 0.0662 mL | 0.1325 mL | 0.265 mL | 0.3312 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Taxezopidines J, K, and L, new taxoids from Taxus cuspidata inhibiting Ca2+-induced depolymerization of microtubules.
Tetrahedron, 1999,55(9):2553-2558.
Three new taxoids, taxezopidine J (1), taxezopidine K (2), and Taxezopidine L (3), have been isolated from seeds of the Japanese yew Taxus cuspidata Sieb. et Zucc. and the structures were elucidated on the basis of spectroscopic data and chemical means. Taxezopidine K (2) and Taxezopidine L (3) markedly inhibited Ca2+-induced depolymerization of microtubules, while taxuspine D (4), a known taxoid from the yew, induced unusual shape change of mitotic spindles like taxol.
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