Bombiprenone

CAS# 21978-49-4

Bombiprenone

Catalog No. BCN4940----Order now to get a substantial discount!

Product Name & Size Price Stock
Bombiprenone: 5mg $615 In Stock
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Quality Control of Bombiprenone

Number of papers citing our products

Chemical structure

Bombiprenone

3D structure

Chemical Properties of Bombiprenone

Cas No. 21978-49-4 SDF Download SDF
PubChem ID 12300193 Appearance Powder
Formula C43H70O M.Wt 603.0
Type of Compound Miscellaneous Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (5E,9E,13E,17E,21E,25E,29E)-6,10,14,18,22,26,30,34-octamethylpentatriaconta-5,9,13,17,21,25,29,33-octaen-2-one
SMILES CC(=CCCC(=CCCC(=CCCC(=CCCC(=CCCC(=CCCC(=CCCC(=CCCC(=O)C)C)C)C)C)C)C)C)C
Standard InChIKey RPUKUBKVRRNJDI-WDXILIIOSA-N
Standard InChI InChI=1S/C43H70O/c1-35(2)19-11-20-36(3)21-12-22-37(4)23-13-24-38(5)25-14-26-39(6)27-15-28-40(7)29-16-30-41(8)31-17-32-42(9)33-18-34-43(10)44/h19,21,23,25,27,29,31,33H,11-18,20,22,24,26,28,30,32,34H2,1-10H3/b36-21+,37-23+,38-25+,39-27+,40-29+,41-31+,42-33+
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Bombiprenone

The fruits of Momordica charantia

Biological Activity of Bombiprenone

DescriptionStandard reference
In vitro

Cytotoxic Compounds from Brucea mollis.[Pubmed: 24106661]

Sci Pharm. 2012 Dec 31;81(3):819-31.


METHODS AND RESULTS:
Ten compounds, including soulameanone (1), isobruceine B (2), 9-methoxy-canthin-6-one (3), bruceolline F (4), niloticine (5), octatriacontan-1-ol (6), Bombiprenone (7), α-tocopherol (8), inosine (9), and apigenin 7-O-β-D-glucopyranoside (10), were isolated from the leaves, stems, and roots of Brucea mollis Wall. ex Kurz. Their structures were determined using one-and two-dimensional NMR spectroscopy and mass spectrometry.
CONCLUSIONS:
All compounds were evaluated for their cytotoxic activity against KB (human carcinoma of the mouth), LU-1 (human lung adenocarcinoma), LNCaP (human prostate adeno-carcinoma), and HL-60 (human promyelocytic leukemia) cancer cell lines.

Bombiprenone Dilution Calculator

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Bombiprenone Molarity Calculator

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Preparing Stock Solutions of Bombiprenone

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.6584 mL 8.2919 mL 16.5837 mL 33.1675 mL 41.4594 mL
5 mM 0.3317 mL 1.6584 mL 3.3167 mL 6.6335 mL 8.2919 mL
10 mM 0.1658 mL 0.8292 mL 1.6584 mL 3.3167 mL 4.1459 mL
50 mM 0.0332 mL 0.1658 mL 0.3317 mL 0.6633 mL 0.8292 mL
100 mM 0.0166 mL 0.0829 mL 0.1658 mL 0.3317 mL 0.4146 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Bombiprenone

Cytotoxic Compounds from Brucea mollis.[Pubmed:24106661]

Sci Pharm. 2012 Dec 31;81(3):819-31.

Ten compounds, including soulameanone (1), isobruceine B (2), 9-methoxy-canthin-6-one (3), bruceolline F (4), niloticine (5), octatriacontan-1-ol (6), Bombiprenone (7), alpha-tocopherol (8), inosine (9), and apigenin 7-O-beta-D-glucopyranoside (10), were isolated from the leaves, stems, and roots of Brucea mollis Wall. ex Kurz. Their structures were determined using one-and two-dimensional NMR spectroscopy and mass spectrometry. All compounds were evaluated for their cytotoxic activity against KB (human carcinoma of the mouth), LU-1 (human lung adenocarcinoma), LNCaP (human prostate adeno-carcinoma), and HL-60 (human promyelocytic leukemia) cancer cell lines. Compound 2 showed significant cytotoxic activity against KB, LU-1, LNCaP, and HL-60 cancer cells with IC50 values of 0.39, 0.40, 0.34, and 0.23 mug/mL, respectively. In addition, compounds 3 and 5 showed significant cytotoxic activity against KB, LU-1, LNCaP, and HL-60 cancer cells with IC50 values around 1-4 mug/mL. Compounds 9-methoxycanthin-6-one (3) and niloticine (5) have been discovered for the first time from the Brucea genus.

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