Uralsaponin CCAS# 1262326-46-4 |
Quality Control & MSDS
3D structure
Package In Stock
Number of papers citing our products
| Cas No. | 1262326-46-4 | SDF | Download SDF |
| PubChem ID | 86278344 | Appearance | Powder |
| Formula | C42H64O16 | M.Wt | 824.95 |
| Type of Compound | Triterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (2S,3S,4S,5R,6R)-6-[(2R,3R,4S,5S,6S)-2-[[(3S,4aR,6aR,6bS,8aR,9R,11R,12aS,14aR,14bS)-9-hydroxy-11-(hydroxymethyl)-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-2,3,4a,5,6,7,8,9,10,12,12a,14a-dodecahydro-1H-picen-3-yl]oxy]-6-carboxy-4,5-dihydroxyoxan-3-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid | ||
| SMILES | CC1(C2CCC3(C(C2(CCC1OC4C(C(C(C(O4)C(=O)O)O)O)OC5C(C(C(C(O5)C(=O)O)O)O)O)C)C(=O)C=C6C3(CCC7(C6CC(CC7O)(C)CO)C)C)C)C | ||
| Standard InChIKey | ZFSRTFFNWLQWAO-UEFFDLHQSA-N | ||
| Standard InChI | InChI=1S/C42H64O16/c1-37(2)21-8-11-42(7)32(20(44)14-18-19-15-38(3,17-43)16-22(45)39(19,4)12-13-41(18,42)6)40(21,5)10-9-23(37)55-36-31(27(49)26(48)30(57-36)34(53)54)58-35-28(50)24(46)25(47)29(56-35)33(51)52/h14,19,21-32,35-36,43,45-50H,8-13,15-17H2,1-7H3,(H,51,52)(H,53,54)/t19-,21-,22+,23-,24-,25-,26-,27-,28+,29-,30-,31+,32+,35-,36+,38+,39+,40-,41+,42+/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1. Uralsaponin C shows the cytotoxic activity against the human cancer cell lines MGC-803, SW620, and SMMC-7721 with IC50 > 100 μmol/L. |
Uralsaponin C Dilution Calculator
Uralsaponin C Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.2122 mL | 6.061 mL | 12.1219 mL | 24.2439 mL | 30.3049 mL |
| 5 mM | 0.2424 mL | 1.2122 mL | 2.4244 mL | 4.8488 mL | 6.061 mL |
| 10 mM | 0.1212 mL | 0.6061 mL | 1.2122 mL | 2.4244 mL | 3.0305 mL |
| 50 mM | 0.0242 mL | 0.1212 mL | 0.2424 mL | 0.4849 mL | 0.6061 mL |
| 100 mM | 0.0121 mL | 0.0606 mL | 0.1212 mL | 0.2424 mL | 0.303 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- INCB3344
Catalog No.:BCC1648
CAS No.:1262238-11-8
- Agrimonolide 6-O-glucoside
Catalog No.:BCN6141
CAS No.:126223-29-8
- Ginsenoside Rg4
Catalog No.:BCN2713
CAS No.:126223-28-7
- LY2886721
Catalog No.:BCC3807
CAS No.:1262036-50-9
- Spiranthol A
Catalog No.:BCN7893
CAS No.:126192-35-6
- Icariside E5
Catalog No.:BCN6140
CAS No.:126176-79-2
- BAPTA-AM
Catalog No.:BCC5456
CAS No.:126150-97-8
- GNF179
Catalog No.:BCC5175
CAS No.:1261114-01-5
- Siamenoside I
Catalog No.:BCN2540
CAS No.:126105-12-2
- 11-Oxo-mogroside V
Catalog No.:BCN2509
CAS No.:126105-11-1
- Rubiyunnanin C
Catalog No.:BCN8045
CAS No.:1261030-04-9
- I-BET-762
Catalog No.:BCC4474
CAS No.:1260907-17-2
- 24-Hydroxy-licoricesaponin A3
Catalog No.:BCN7896
CAS No.:1262326-47-5
- Uralsaponin D
Catalog No.:BCN7895
CAS No.:1262489-44-0
- (2R,3S)-Dihydrodehydroconiferyl alcohol
Catalog No.:BCN7886
CAS No.:126253-41-6
- Fumitremorgin B
Catalog No.:BCN6453
CAS No.:12626-17-4
- Assamicadine
Catalog No.:BCN1957
CAS No.:126260-96-6
- GS967
Catalog No.:BCC6401
CAS No.:1262618-39-2
- Benzoylmesaconine hydrochloride
Catalog No.:BCN5399
CAS No.:126266-38-4
- Penitrem A
Catalog No.:BCC7957
CAS No.:12627-35-9
- Trigonosin F
Catalog No.:BCN6403
CAS No.:1262842-73-8
- 25-Hydroxy VD2-D6
Catalog No.:BCC1305
CAS No.:1262843-46-8
- CCT241533
Catalog No.:BCC1462
CAS No.:1262849-73-9
- Spautin-1
Catalog No.:BCC6420
CAS No.:1262888-28-7
Chemical constituents of triterpenoid saponins from Glycyrrhiza uralensis.
Chinese Traditional & Herbal Drugs, 2013, 44(12):1552-1557.
To study the chemical constituents from the roots and rhizomes of Glycyrrhiza uralensis. Methods: The compounds were separated and purified by solvent and chromatographic methods. Their structures were identified by spectroscopic techniques. Results: Fourteen triterpenoid saponins isolated from 50% ethanol extract of the roots and rhizomes of G. uralensis were identified as Uralsaponin C (1), uralsaponin D (2), licorice-saponin A3 (3), uralsaponin F (4), 22β-acetoxyl-glycyrrizin (5), 24-hydroxyl-licorice-saponin E2 (6), licorice-saponin E2 (7), licorice-saponin G2 (8), 22β-acetoxyl-glyrrhaldehyde (9), 3β-O-[β-D-glucuronopyranosyl-(1→2) - β-D-glucuronopyranosyl]-glycyrretol (10), araboglycyrrhizin (11), licorice-saponin J2 (12), glycyrrhizin (13), and glycyrrhetic acid monoglucuronide (14). Compounds 1-14 showed the cytotoxic activity against the human cancer cell lines MGC-803, SW620, and SMMC-7721 with IC50 > 100 μmol/L. The aglycones of compounds 2, 6-8, and 13 displayed the inhibition on the growth of cancer cells with IC50 at 18.3-41.6 μmol/L. Conclusion: Compound 14 is a new natural product, and compound 11 is isolated from the plant for the first time; Compounds 1-14 show no cytotoxic activity against the human cancer cell lines MGC-803, SW620, and SMMC-7721, and the aglycones of compounds 2, 6-8, and 13 could significantly increase the cytotoxic activity after hydrolysis.
