Venoterpine

CAS# 17948-42-4

Venoterpine

Catalog No. BCN3422----Order now to get a substantial discount!

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Quality Control of Venoterpine

Number of papers citing our products

Chemical structure

Venoterpine

3D structure

Chemical Properties of Venoterpine

Cas No. 17948-42-4 SDF Download SDF
PubChem ID 56842090 Appearance Oil
Formula C9H11NO M.Wt 149.2
Type of Compound alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (6R,7S)-7-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-6-ol
SMILES CC1C(CC2=C1C=NC=C2)O
Standard InChIKey IOIGOIPHPUCFOB-IMTBSYHQSA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Venoterpine

The roots of Rauvolfia verticillata

Biological Activity of Venoterpine

DescriptionVenoterpine is a natural product from Rauvolfia verticillata.

Protocol of Venoterpine

Structure Identification
Journal of Natural Products , 1982 , 45 (4) :489-494.

Alcaloïdes Des écorces De Tiges De Strychnos dinklagei[Reference: WebLink]


METHODS AND RESULTS:
Ten alkaloids have been isolated from the stem barks of Strychnos dinklagei. Six of them are known compounds, two monoterpene alkaloids: gentianine (3) and Venoterpine (4), and four pyrido [4, 3b] carbazoles: ellipticine (1), N b-oxy-ellipticine (5), 3,14-dihydroellipticine (6) and 3,14,4,21-tetrahydroellipticine (7). The four other alkaloids are new natural ellipticine derivatives: 17-oxoellipticine (2), 10-hydroxyellipticine (8), N b-oxy 17-oxoellipticine (9) and 18-hydroxyellipticine (10).
CONCLUSIONS:
Their structures have been established by spectral analysis and chemical correlations. In addition three neutral products have been isolated and identified: methyl syringate (12), lirioresinol A (13) and lirioresinol B (14).

Venoterpine Dilution Calculator

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Venoterpine Molarity Calculator

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Preparing Stock Solutions of Venoterpine

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 6.7024 mL 33.5121 mL 67.0241 mL 134.0483 mL 167.5603 mL
5 mM 1.3405 mL 6.7024 mL 13.4048 mL 26.8097 mL 33.5121 mL
10 mM 0.6702 mL 3.3512 mL 6.7024 mL 13.4048 mL 16.756 mL
50 mM 0.134 mL 0.6702 mL 1.3405 mL 2.681 mL 3.3512 mL
100 mM 0.067 mL 0.3351 mL 0.6702 mL 1.3405 mL 1.6756 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Venoterpine

A New Ajmaline-type Alkaloid from the Roots of Rauvolfia serpentina.[Pubmed:30520580]

Nat Prod Commun. 2017 Apr;12(4):495-498.

A new ajmaline-type alkaloid, 21-Omicron-methylisoajmaline (1), together with twenty-one known compounds, a mixture of beta-sitosterol (2) and stigmasterol (3), reserpinine (4); tetrahydroalstonine (5), reserpine (6), Venoterpine (7), yohimbine (8), 6'-O-(3,4,5-trimethoxybenzoyl)glomeratose A (9), isoajmaline (10), 3-epi-alpha-yohimbine (11), methyl 3,4,5-trimethoxy-trans-cinnamate (12), a mixture of beta-sitosterol 3-Omicron-beta-D-glucopyranoside (13) and stigmasterol 3-Omicron-beta-D- glucopyranoside (14), rescidine (15), 7-deoxyloganic acid (16), ajmaline (17), suaveoline (18), (+)-tetraphyllicine (19), loganic acid (20), 3-hydroxysarpagine (21), and sarpagine (22), were isolated from the roots of Rauvolla serpentina. Their structures were elucidated by spectroscopic data analysis and comparison with literature data. Compounds 11, 12 and 15 were for the first time identified from the genus Rauvolfla and 5, 7, 11, 12, 15, 18 and 22 were found from R. sepentina for the first time. Compound 11 showed moderate anticholinesterase activity with IC(5)(0) value of 15.58 muM, whereas 6 exhibited strong vasorelaxant activity with the EC(5)(0) value of 0.05 muM.

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