Yashabushidiol ACAS# 52393-53-0 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
Cas No. | 52393-53-0 | SDF | Download SDF |
PubChem ID | N/A | Appearance | Oil |
Formula | C19H24O2 | M.Wt | 284.4 |
Type of Compound | Phenols | Storage | Desiccate at -20°C |
Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. |
Yashabushidiol A Dilution Calculator
Yashabushidiol A Molarity Calculator
1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
1 mM | 3.5162 mL | 17.5809 mL | 35.1617 mL | 70.3235 mL | 87.9044 mL |
5 mM | 0.7032 mL | 3.5162 mL | 7.0323 mL | 14.0647 mL | 17.5809 mL |
10 mM | 0.3516 mL | 1.7581 mL | 3.5162 mL | 7.0323 mL | 8.7904 mL |
50 mM | 0.0703 mL | 0.3516 mL | 0.7032 mL | 1.4065 mL | 1.7581 mL |
100 mM | 0.0352 mL | 0.1758 mL | 0.3516 mL | 0.7032 mL | 0.879 mL |
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. |
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- 2'-Hydroxy-3',4',6'-trimethoxychalcone
Catalog No.:BCN0522
CAS No.:91856-16-5
- 2'-Hydroxy-3',4',6'-trimethoxydihydrochalcone
Catalog No.:BCN0521
CAS No.:1222818-87-2
- 5,6,7,4'-Tetramethoxyflavanone
Catalog No.:BCN0520
CAS No.:72943-90-9
- 5,7,8-Trimethoxyflavanone
Catalog No.:BCN0519
CAS No.:69616-73-5
- Grandiuvarin A
Catalog No.:BCN0518
CAS No.:882692-93-5
- Desacetylripariochromene B
Catalog No.:BCN0517
CAS No.:69790-24-5
- (R)-5-Hydroxy-7-(4-hydroxyphenyl)-1-phenylheptan-3-one
Catalog No.:BCN0516
CAS No.:1961196-24-6
- Alpinin B
Catalog No.:BCN0515
CAS No.:2125947-85-3
- Myricetin 3-O-beta-D-xylopyranosyl(1-2)-[alpha-L-rhamnopyranosyl-(1-6)]-beta-D-glucopyranoside
Catalog No.:BCN0514
CAS No.:
- Linarin 4'''-acetate
Catalog No.:BCN0513
CAS No.:79541-06-3
- Methyl epi-dihydrophaseate
Catalog No.:BCN0512
CAS No.:57761-30-5
- (3R,5R)-1-(4-Hydroxy-3-methoxyphenyl)-7-(3,4-dihydroxyphenyl)heptane-3,5-diol
Catalog No.:BCN0511
CAS No.:408324-13-0
- Dihydrokaempferide
Catalog No.:BCN0524
CAS No.:137225-59-3
- 5-Hydroxy-7-(4-hydroxy-3-methoxyphenyl)-1-phenylhept-4-en-3-one
Catalog No.:BCN0525
CAS No.:142831-06-9
-
Ganoderic Acid T
Catalog No.:BCN0526
CAS No.:103992-91-2
- 7-(4-Hydroxyphenyl)-5-methoxy-1-phenylheptan-3-one
Catalog No.:BCN0527
CAS No.:100667-53-6
- 7-(4-Hydroxy-3-methoxyphenyl)-5-methoxy-1-phenylheptan-3-one
Catalog No.:BCN0528
CAS No.:83161-95-9
- Nudaurine
Catalog No.:BCN0529
CAS No.:402469-62-9
- Amurine
Catalog No.:BCN0530
CAS No.:4984-99-0
- (+)-Yashabushidiol B
Catalog No.:BCN0531
CAS No.:103729-38-0
- 3-Deoxy-11,13-dihydroisosecotanapartholide
Catalog No.:BCN0532
CAS No.:572924-43-7
- Methyl 2-(2-hydroxyphenyl)acetate
Catalog No.:BCN0533
CAS No.:22446-37-3
- (R)-5-Hydroxy-7-(4-hydroxy-3-methoxyphenyl)-1-phenylheptan-3-one
Catalog No.:BCN0534
CAS No.:68622-73-1
- Tsaokoarylone
Catalog No.:BCN0535
CAS No.:811471-20-2
Two-Pot Synthesis of Chiral 1,3-syn-Diols through Asymmetric Organocatalytic Aldol and Wittig Reactions Followed by Domino Hemiacetal/Oxy-Michael Reactions.[Pubmed:29322570]
Chemistry. 2018 Apr 3;24(19):4909-4915.
A two-pot synthetic method to construct the chiral syn-1,3-diol unit has been developed from three aldehydes and either Wittig or Horner-Wadsworth-Emmons reagents. In the first pot, chiral delta-hydroxy alpha,beta-unsaturated ketones are synthesized with excellent enantioselectivity by the organocatalyst-mediated asymmetric direct aldol reaction of two different aldehydes, followed by either Wittig or Horner-Wadsworth-Emmons reactions. In the second pot, domino acetalization with an aldehyde and subsequent oxy-Michael reaction proceeds in the presence of NaClO4 and a catalytic amount of Bi(OTf)3 (OTf=trifluoromethanesulfonate) to provide the chiral 1,3-syn-diol derivative with excellent diastereoselectivity. Diospongin C and Yashabushidiol A have been synthesized efficiently by using the present method as a key step.
Interactions of Desmethoxyyangonin, a Secondary Metabolite from Renealmia alpinia, with Human Monoamine Oxidase-A and Oxidase-B.[Pubmed:29138643]
Evid Based Complement Alternat Med. 2017;2017:4018724.
Renealmia alpinia (Zingiberaceae), a medicinal plant of tropical rainforests, is used to treat snakebites and other injuries and also as a febrifuge, analgesic, antiemetic, antiulcer, and anticonvulsant. The dichloromethane extract of R. alpinia leaves showed potent inhibition of human monoamine oxidases- (MAOs-) A and B. Phytochemical studies yielded six known compounds, including pinostrobin 1, 4'-methyl ether sakuranetin 2, sakuranetin 3, pinostrobin chalcone 4, Yashabushidiol A 5, and desmethoxyyangonin 6. Compound 6 displayed about 30-fold higher affinity for MAO-B than MAO-A, with Ki values of 31 and 922 nM, respectively. Kinetic analysis of inhibition and equilibrium-dialysis dissociation assay of the enzyme-inhibitor complex showed reversible binding of desmethoxyyangonin 6 with MAO-A and MAO-B. The binding interactions of compound 6 in the active site of the MAO-A and MAO-B isoenzymes, investigated through molecular modeling algorithms, confirmed preferential binding of desmethoxyyangonin 6 with MAO-B compared to MAO-A. Selective reversible inhibitors of MAO-B, like desmethoxyyangonin 6, may have important therapeutic significance for the treatment of neurodegenerative disorders, such as Parkinson's disease and Alzheimer's disease.
Constituents of Fermented Male Flowers of Alnus sieboldiana (Betulaceae).[Pubmed:30549825]
Nat Prod Commun. 2017 Jan;12(1):57-58.
Fractionation of the ethyl acetate crude extract of the fermented male flowers of Alnus sieboldiana resulted in the isolation of two diaryiheptanoids and six flavonoids. Yashabushidiol A, yashabushidiol B and naringenin were known constituents of the male flowers of A. sieboldiana while kaenipferol, quercetin, pinocembrin dimethyl ether, 5,7-dimethoxy-3-hydroxyflavanone and 5,7-dimethoxy-3-hydroxyflavone were isolated for first time from the fermented mile flowers of A. sieboldiana. The isolated compounds were characterized using NMR and HRMS and compared with available literature. -.
Synthesis of yashabushidiol and its analogues and their cytotoxic activity against cancer cell lines.[Pubmed:19410455]
Bioorg Med Chem Lett. 2009 Jun 1;19(11):3125-7.
A total synthesis of yashabushidiol (1a), a linear diarylheptanoid having 1,3- diol system and its analogues has been achieved by alkynylation of 3-hydroxy-5-phenyl pentanal with substituted phenyl acetylenes. All the compounds have shown significant anti-proliferative activity on human leukemia (THP-1, U-937) and melanoma (A-375) cell lines. Compounds 2a and 2b were found to be most potent with an IC(50) of 12.82 microg/mL and 12.62 microg/mL, respectively, on THP-1 leukemia cell line.