Cancer Immunology

Cancer Immunology refers to the relationship between immune function and cancer. The immunological mechanisms involved in cancer growth are highly complex and provide numerous potential points for intervention with small molecules, including extracellular enzymes, receptors and intracellular signal transduction pathways.

Cancer Immunology Products Targets

Products for Cancer Immunology - Page 7

Cat.No. Product Name Information/Activity
BCC6333 Purotoxin 1 1396322-38-5
BCC6966 MRS 2219 14141-47-0
BCC3715 A66 A66 is a highly specific and selective p110α inhibitor with an IC50 of 32 nM.
BCC4988 AS-252424 AS-252424 is a potent and selective PI3Kγ inhibitor with an IC50 of 30±10 nM.
BCC2495 AS-605240 AS-605240 is a specific and orally active inhibitor of the PI3Kγ, with an IC50 of 8 nM, and a Ki of 7.8 nM.
BCC2523 AZD6482 AZD 6482 (KIN-193) is a potent and selective p110β inhibitor with an IC50 of 0.69 nM.
BCC1813 NVP-BAG956 NVP-BAG956 is an ATP-competitive PI3K inhibitor with IC50s of 34, 56, 112 and 444 nM for PI3Kδ, PI3Kα, PI3Kγ and PI3Kβ, respectively.
BCC1507 CZC24832 CZC24832 is a highly selective and potent PI3Kγ inhibitor (IC50=27 nM) with apparent dissociation constants (Kdapp) of 19 nM.
BCC4984 GSK1059615 GSK1059615 is a dual inhibitor of PI3Kα/β/δ/γ (reversible) and mTOR with IC50 of 0.4 nM/0.6 nM/2 nM/5 nM and 12 nM, respectively.
BCC1110 KU-0060648 KU-0060648 is a dual inhibitor of PI3K and DNA-PK with IC50s of 4 nM, 0.5 nM, 0.1 nM, 0.594 nM and 8.6 nM for PI3Kα, PI3Kβ, PI3Kγ, PI3Kδ and DNA-PK, respectively.