Cell Cycle Inhibitor
Cell cycle inhibitors slow or stop cell cycle progression through various mechanisms. Cell cycle arrest can be induced at different stages, decreasing the rate of cell division and the number of actively cycling cells.
Products for Cell Cycle Inhibitor
- Cat.No. Product Name Information/Activity
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BCC4914
Itraconazole
Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ~800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects.
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BCC1050
10058-F4
10058-F4 is a c-Myc inhibitor that prevents c-Myc-Max dimerization and transactivation of c-Myc target gene expression.
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BCC1085
ABT-751 (E7010)
ABT-751(E 7010) is a novel bioavailable tubulin-binding and antimitotic sulfonamide agent with IC50 of about 1.5 and 3.4 μM in neuroblastoma and non-neuroblastoma cell lines, respectively.
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BCC3689
AZD-5438
AZD-5438 is a potent CDK1, CDK2, and CDK9 inhibitor, with IC50s of 16 nM, 6 nM, and 20 nM in cell-free assays, respectively. AZD-5438 shows less inhibition activity against GSK3β, CDK5 and CDK6 .
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BCN5599
Baicalein
Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase inhibitor with an IC50 value of 3.12 mM.
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BCC8017
CFM 4
331458-02-7
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BCC7935
8-Chloroadenosine
34408-14-5
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BCC4099
CPI-203
CPI-203 is a novel potent, selective and cell permeable inhibitor of BET bromodomain, with an IC50 value of appr 37 nM (BRD4 α-screen assay).
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BCN5590
Daidzein
Daidzein is a soy isoflavone, which acts as a PPAR activator.
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BCC1306
3,3'-Diindolylmethane
3,3'-Diindolylmethane is a strong, pure androgen receptor (AR) antagonist.
