Cardiovascular System Research
The cardiovascular, or circulatory, system is a closed elastic circuit consisting of the heart, blood vessels (arteries, capillaries and veins) and the blood. The primary function is to pump oxygenated blood to the tissues throughout the body and reabsorb waste carbon dioxide for its removal. This function is performed by the use of pulmonary and systemic circulation.
Cardiovascular System Research Products Areas
Products for Cardiovascular System Research - Page 16
- Cat.No. Product Name Information/Activity
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BCC6279
FSLLRY-NH2
245329-02-6
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BCC7433
RWJ 56110
252889-88-6
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BCC7125
SCH 79797 dihydrochloride
SCH79797 dihydrochloride is a highly potent, selective nonpeptide protease activated receptor 1 (PAR1) antagonist. SCH79797 dihydrochloride inhibits binding of a high-affinity thrombin receptor-activating peptide to PAR1 with an IC50 of 70 nM and a Ki of 35 nM. SCH79797 dihydrochloride inhibits thrombin-induced platelet aggregation with an IC50 of 3 μM. SCH79797 dihydrochloride has antiproliferative and pro-apoptotic effects, and limits myocardial ischemia/reperfusion injury in rat hearts. SCH79797 dihydrochloride also potently prevents PAR1 activation in vascular smooth muscle cells, endothelial cells, and astrocytes.
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BCC5770
tcY-NH2
327177-34-4
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BCC6281
Q94 hydrochloride
1052076-77-3
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BCC7392
APC 366
Tryptase inhibitor
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BCC2096
Gabexate mesylate
Gabexate mesylate is a Factor X inhibitor; serine protease inhibitor .
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BCC3642
ML161
Parmodulin 2 (ML161) is an allosteric inhibitor of protease-activated receptor 1 (PAR1) with an IC50 of 0.26 μM. Parmodulin 2 is a potent and non-competitive inhibitor of SFLLRN-induced P-selectin expression leading to inhibition of platelet aggregation in vitro and platelet thrombus formation in vivo.
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BCC6041
Parstatin (human)
1065755-99-8
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BCC6042
Parstatin (mouse)
1065756-01-5


