Cardiovascular System Research

The cardiovascular, or circulatory, system is a closed elastic circuit consisting of the heart, blood vessels (arteries, capillaries and veins) and the blood. The primary function is to pump oxygenated blood to the tissues throughout the body and reabsorb waste carbon dioxide for its removal. This function is performed by the use of pulmonary and systemic circulation.

Cardiovascular System Research Products Areas

Products for Cardiovascular System Research - Page 72

  1. Cat.No. Product Name Information/Activity
  2. BCC5860 6-Iodonordihydrocapsaicin Potent, competitive vanilloid receptor antagonist 6-Iodonordihydrocapsaicin chemical structure
  3. BCC7031 5'-Iodoresiniferatoxin 535974-91-5 5'-Iodoresiniferatoxin chemical structure
  4. BCC7668 JNJ 17203212 JNJ-17203212 is a novel and selective TRPV1 antagonist, with IC50 of 65 nM and 102 nM for human TRPV1 and rat TRPV1. JNJ 17203212 chemical structure
  5. BCC5779 L-R4W2 206350-79-0 L-R4W2 chemical structure
  6. BCC7770 RN 1734 RN-1734 is selective antagonist of the TRPV4 channel, completely antagonizes 4αPDD-mediated activation of TRPV4 with comparable, low micromolar IC50s for all three species (hTRPV4: 2.3 μM, mTRPV4: 5.9 μM, rTRPV4: 3.2 μM). RN-1734 clearly decreases the production of tumor necrosis factor α (TNF-α) and interleukin 1β (IL-1β) without altering the number of olig2-positive cells. RN 1734 chemical structure
  7. BCC7128 SB 366791 SB-366791 is a potent , competitive and selective vanilloid receptor (VR1/TRPV1) antagonist with IC50 of 5.7±1.2 nM target: VR1/TRPV1 IC 50: 5.7±1.2 nM [1] SB-366791 produced a concentration-dependent inhibition of the response to capsaicin with an apparent pKb of 7.74±0.08. SB 366791 chemical structure
  8. BCC7620 SB 452533 459429-39-1 SB 452533 chemical structure
  9. BCN5564 alpha-Spinasterol α-Spinasterol, isolated from Spinacia oleracea, has antibacterial activity. α-Spinasterol is a transient receptor potential vanilloid 1 (TRPV1) antagonist, has anti-inflammatory, antidepressant, antioxidant and antinociceptive effects. α-Spinasterol inhibits COX-1 andCOX-2 activities with IC50 values of 16.17 μM and 7.76 μM, respectively. alpha-Spinasterol chemical structure
  10. BCC2514 Tranilast Tranilast is an antiallergic agent. Tranilast chemical structure
  11. BCC6114 MM-22 956605-71-3 MM-22 chemical structure

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