Others Products Targets
- Oxidative Phosphorylation (6)
- NHE (3)
- Monocarboxylate Transporter (3)
- Matrix Metalloprotease (16)
- LXR-like Receptor (6)
- Voltage-gated Sodium (NaV) Channel (30)
- Voltage-gated Potassium (KV) Channel (38)
- Voltage-gated Calcium Channel (CaV) (38)
- Cell Adhesion Molecule (21)
- TRPV (30)
- Lipoxygenase (8)
- Bradykinin Receptor (12)
- Others (16)
- Cyclooxygenase (24)
- Apelin Receptor (5)
- TRPP (3)
- TRPML (3)
- TRPC (4)
- TRPA1 (7)
- Glycine Receptor (6)
- Epithelial Sodium Channel (3)
- STIM-Orai Channel (4)
- Ryanodine Receptor (6)
- Angiotensin-Converting Enzyme (8)
- 5-HT3 Receptor (39)
- IP3 Receptor (2)
- TRPM (8)
- Acid-Sensing Ion Channel (3)
- Calcium-Activated Potassium (KCa) Channel (19)
- VIP Receptor (7)
- Inward Rectifier Potassium (Kir) Channel (21)
- Stearoyl-CoA 9-Desaturase (1)
- Vasopressin Receptor (6)
- NADPH Oxidase (2)
- Monoamine Oxidase (10)
- Heme Oxygenase (2)
- NO donors and precursors (9)
- nNOS (5)
- iNOS (11)
- eNOS (1)
- Sodium and Potassium ATPase (3)
- KCC2 (1)
- H+-ATPase (3)
- Urotensin-II Receptor (8)
- H+,K+-ATPase (4)
- Ionophore (6)
- Chloride Channel (17)
- ETB Receptor (6)
- ETA Receptor (5)
- Angiotensin AT2 Receptor (3)
- Angiotensin AT1 Receptor (9)
- M5 Receptor (2)
- M4 Receptor (3)
- M3 Receptor (4)
- Purinergic (P2Y) Receptor (31)
- M2 Receptor (5)
- M1 Receptor (8)
- NCX (5)
- Ca2+-ATPase (7)
- Purinergic (P2X) Receptor (32)
- NKCC (2)
- Adrenergic α2 Receptor (33)
- Adrenergic α1 Receptor (22)
- HCN Channel (4)
- Adrenergic β3 Receptor (12)
- Adrenergic β2 Receptor (6)
- Adrenergic β1 Receptor (7)
- Protease-Activated Receptor (23)
- Prostanoid Receptor (24)
- Platelet-Activating Factor (PAF) Receptor (5)
- Phosphodiesterase (34)
Products for Others - Page 38
- Cat.No. Product Name Information/Activity
-
BCC5248
PPQ-102
PPQ-102 is a potent CFTR inhibitor which can completely inhibited CFTR chloride current with IC50 of ~90 nM.
-
BCC6220
T16Ainh - A01
T16Ainh-A01, an aminophenylthiazole, is a potent transmembrane protein 16A (TMEM16A) inhibitor, inhibiting TMEM16A-mediated chloride currents with an IC50 value of ~1 µM. TMEM16A (ANO1) functions as a calcium-activated chloride channel (CaCC).
-
BCC7391
Talniflumate
66898-62-2
-
BCC7578
KM 11060
KM11060 is a novel corrector of the F508del-CFTR trafficking defect.
-
BCC7820
PG 01
PG01 is a potent CFTR Cl- channel potentiator. PG01 can correct gating defects of CFTR mutants, is effective on b>E193K
-
BCC6980
A23187, free acid
Calcimycin (A-23187) is an antibiotic and a unique divalent cation ionophore (like calcium and magnesium). Calcimycin induces Ca2+-dependent cell death by increasing intracellular calcium concentration. Calcimycin inhibits the growth of Gram-positive bacteria and some fungi. Calcimycin also inhibits the activity of ATPase and uncouples oxidative phosphorylation of mammalian cells. Calcimycin induces apoptosis.
-
BCC5805
Ionomycin calcium salt
Ionomycin calcium (SQ23377 calcium) is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. Ionomycin calcium (SQ23377 calcium) is highly specific for divalent cations (Ca>Mg>Sr=Ba). Ionomycin (SQ23377) promotes apoptosis. Ionomycin calcium (SQ23377 calcium) also induces the activation of protein kinase C (PKC).
-
BCC7261
Ionomycin free acid
Ionomycin (SQ23377) is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. Ionomycin (SQ23377) is highly specific for divalent cations (Ca>Mg>Sr=Ba). Ionomycin (SQ23377) promotes apoptosis. Ionomycin also induces the activation of protein kinase C (PKC).
-
BCC5319
Sodium Monensin
Monensin sodium salt is an antibiotic secreted by the bacteria Streptomyces cinnamonensis. Monensin sodium salt is an ionophore that mediates Na+/H+ exchange.
-
BCC7388
Nonactin
Nonactin is a naturally occurring macrotetrolide antibiotic from Streptomyces griseus. Nonactin acts as an ionophore for monovalent cations, including K+, and NH4+. Nonactin is able to uncouple the oxidative phosphorylation of mitochondria. Nonactin selectively induces apoptosis in cell lines harboring active mutant β-catenin. Nonactin inhibits the surface expression of endogenous HSP60.
