Bombesin Receptor

Bombesin receptors are activated by the endogenous ligands gastrin-releasing peptide (GRP), neuromedin B (NMB) and GRP18-27 (neuromedin C). Three subtypes of bombesin receptor are known: BB1, BB2 and an orphan receptor (bb3).

Products for Bombesin Receptor

Cat.No. Product Name Information/Activity
BCC5933 BIM 187 137734-88-4
BCC5708 Bombesin Bombesin is a tetradecapeptide originally isolated from frog skin; plays an important role in the release of gastrin and the activation of G-protein receptors.
BCC5810 GRP (human) Gastrin-Releasing Peptide, human (GRP) belongs to the bombesin-like peptide family, and is not a classical hypothalamic-hypophyseal regulatory hormone since it plays only a perfunctory role in the mediation of pituitary hormone release.
BCC5809 GRP (porcine) 74815-57-9
BCC5934 BIM 189 142062-55-3
BCC5998 BIM 23042 Selective neuromedin B receptor antagonist (NMB-R, BB<sub>1</sub>)
BCC5844 [D-Phe12]-Bombesin 108437-87-2
BCC6020 [D-Phe12,Leu14]-Bombesin 108437-88-3
BCC7426 PD 176252 PD176252 is a potent antagonist of neuromedin-B preferring (BB1) and gastrin-releasing peptide-preferring (BB2) receptor with Kis of 0.17 nM and 1 nM for human BB1 and BB2 receptors, and 0.66 nM, 16 nM for Rat BB1 and BB2 receptors, respectively; PD176252 is also an agonist of N-Formyl peptide receptor1/2 (FPR1/FPR2), with EC50s of 0.31 and 0.66 μM in HL-60 cells.
BCC7203 Alytesin 31078-12-3