Immunology Research
Immunology is a branch of science that studies all aspects of the immune system, ranging from normal physiological functioning through to malfunctions which can lead to immunological diseases. Disorders that result from aberrant activation of the immune system are termed autoimmune diseases.
Immunology Research Products Areas
Products for Immunology Research - Page 33
- Cat.No. Product Name Information/Activity
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BCC7710
Kaliotoxin
145199-73-1
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BCC6307
NS 6180
NS6180 is a novel potent and selective KCa3.1 channel inhibitor(IC50= 9 nM) prevents T-cell activation and inflammation.
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BCC7235
Paxilline
Paxilline is an indole alkaloid mycotoxin from Penicillium paxilli, acts as a potent BK channels inhibitor by an almost exclusively closed-channel block mechanism. Paxilline also inhibits the sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) with IC50s between 5 μM and 50 μM for differing isoforms. Paxilline possesses significant anticonvulsant activity.
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BCC1122
TRAM-34
TRAM-34 is a highly selective blocker of intermediate-conductance calcium-activated K+ channel (IKCa1) (Kd=20 nM).
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BCC8038
TRAM 39
Potent K<sub>Ca</sub>3.1 blocker
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BCC7016
UCL 1684
199934-16-2
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BCC7446
UCL 2077
UCL 2077 is a selective slow-afterhyperpolarization (sAHP) channel blocker (IC50 = 500 nM in hippocampal neurons in culture), having minimal effects on Ca2+ channels, action potentials, input resistance and the medium after hyperpolarization. UCL 2077 is also a subtype-selective blocker of the epilepsy associated KCNQ channels.
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BCC6223
ACHP
406208-42-2
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BCC1423
BMS-345541
BMS-345541 hydrochloride is a selective inhibitor of the catalytic subunits of IKK (IKK-2 IC50=0.3 μM, IKK-1 IC50=4 μM). BMS-345541 binds at an allosteric site of IKK.
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BCC6130
PF 184
1187460-81-6
