Glucocorticoid Receptor
Glucocorticoid receptors (GRs) are nuclear hormone receptors of the NR3C class, which also includes mineralocorticoid, progesterone and androgen receptors. They exist as homodimers coupled to Hsp90 or HMGB proteins, which are shed upon activation.
Products for Glucocorticoid Receptor
- Cat.No. Product Name Information/Activity
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BCN2203
Corticosterone
Corticosterone is an adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid.
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BCC4907
Fluticasone propionate
Fluticasone propionate is a high affinity, selective GR (glucocorticoid receptor) agonist which is derived from fluticasone used to treat asthma and allergic rhinitis.
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BCC6115
GSK 9027
1229096-88-1
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BCC2256
Methylprednisolone
Methylprednisolone is a synthetic corticosteroid with anti-inflammatory and immunomodulating properties.
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BCC4801
Mometasone furoate
Mometasone furoate, prodrug of the free form mometasone, is a agent with high affinity for the glucocorticoid receptor.
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BCC4486
Mifepristone
Mifepristone is a progesterone receptor (PR) and glucocorticoid receptor (GR) antagonist with IC50s of 0.2 nM and 2.6 nM in in vitro assay.
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BCC4767
Budesonide
Budesonide is a glucocortical steroid with potent anti-inflammatory activity.
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BCC1184
Dexamethasone (DHAP)
Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18L expression on monocytes.
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BCN2192
Hydrocortisone
Hydrocortisone is a steroid hormone or glucocorticoid produced by the adrenal gland.
