Leukotriene and Related Receptor
Leukotriene and related receptors are activated by the endogenous ligands leukotriene (LT) B4, LTC4, LTD4, LTE4 and 12-HETE. Leukotrienes are lipid mediators synthesized from arachidonic acid by lipoxygenase enzymes. They are important in inflammatory signaling pathways.
Products for Leukotriene and Related Receptor
- Cat.No. Product Name Information/Activity
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BCC7576
BAY-u 9773
Dual CysLT<sub>1</sub> and CysLT<sub>2</sub> antagonist
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BCC7244
Cinalukast
128312-51-6
-
BCC7310
FPL 55712
40785-97-5
-
BCC7334
MK 571
MRP1 inhibitor; also CysLT<sub>1</sub> (LTD<sub>4</sub>) inverse agonist
-
BCC4680
Montelukast Sodium
Montelukast (sodium) (MK0476) is a potent, selective CysLT1 receptor antagonist.
-
BCC4827
Pranlukast
Pranlukast is a highly potent, selective and competitive antagonist of peptide leukotrienes. Pranlukast inhibits [3H]LTE4, [3H]LTD4, and [3H]LTC4 bindings to lung membranes with Kis of 0.63±0.11, 0.99±0.19, and 5640±680 nM, respectively.
-
BCC7180
SR 2640 hydrochloride
146662-42-2
-
BCC6274
Gue 1654
397290-30-1
-
BCN2215
Arachidonic acid
Arachidonic acid is an essential fatty acid and a major constituent of biomembranes.
-
BCC6038
BAY-X 1005
Veliflapon (BAY X 1005; DG-031) is an orally active and selective 5-lipoxygenase activating protein (FLAP) inhibitor. Veliflapon inhibits the synthesis of the leukotrienes B4 and C4.
