Retinoid X Receptor
Retinoid X receptors (RXR) are members of the NR2B nuclear receptor family and are common binding partners to many other nuclear receptors, including PPARs, liver X receptors (LXRs) and vitamin D receptors (VDRs). There are three RXR subtypes; α , β and γ .
Products for Retinoid X Receptor
- Cat.No. Product Name Information/Activity
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BCC3737
Bexarotene
Bexarotene (LGD1069) is a selective retinoid X receptors (RXR) agonist for the treatment of cutaneous T-cell lymphoma.
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BCC7637
CD 3254
CD3254 a potent and selective retinoid-X-receptor (RXR) agonist.
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BCC6110
Fluorobexarotene
Fluorobexarotene (compound 20) is a potent retinoid-X-receptor (RXR) agonist, with a Ki value of 12 nM and an EC50 value of 43 nM for RXRα receptor. Fluorobexarotene possesses an apparent RXR binding affinity that is 75% greater than Bexarotene.
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BCC2284
Isotretinoin
Isotretinoin(13-cis-Retinoic acid) is a medication used for the treatment of severe acne.
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BCN2185
Retinoic acid
Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM.
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BCC7681
SR 11237
146670-40-8
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BCC6082
HX 531
188844-34-0
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BCC8005
PA 452
PA452, retinoic X receptor (RXR) specific antagonist, inhibits the effect of Retinoic acid (RA) on Th1/Th2 development.
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BCC7638
UVI 3003
UVI 3003 is a highly selective antagonist of retinoid X receptor (RXR), and inhibits xenopus and human RXRα in Cos7 cells, with IC50s of 0.22 and 0.24 μM, respectively.
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BCC7696
LG 101506
331248-11-4
