Products for
Others
- Page 8
-
BCC2256
Methylprednisolone
Methylprednisolone is a synthetic corticosteroid with anti-inflammatory and immunomodulating properties.
-
BCC4801
Mometasone furoate
Mometasone furoate, prodrug of the free form mometasone, is a agent with high affinity for the glucocorticoid receptor.
-
BCC4486
Mifepristone
Mifepristone is a progesterone receptor (PR) and glucocorticoid receptor (GR) antagonist with IC50s of 0.2 nM and 2.6 nM in in vitro assay.
-
BCC4767
Budesonide
Budesonide is a glucocortical steroid with potent anti-inflammatory activity.
-
BCC1184
Dexamethasone (DHAP)
Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18L expression on monocytes.
-
BCN2192
Hydrocortisone
Hydrocortisone is a steroid hormone or glucocorticoid produced by the adrenal gland.
-
BCC4762
Azathioprine
Azathioprine(Azasan, Imuran; BW 57-322) is a drug that suppresses the immune system and is used in organ transplantation and autoimmune disease.
-
BCC4773
Cyclosporin A
Cyclosporin A is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of calcineurin with an IC50 of 5 nM. Cyclosporin A also inhibits CD11a/CD18 adhesion.
-
BCC4952
Tacrolimus (FK506)
Tacrolimus (FK506), a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties.
-
BCN3894
Gliotoxin
Gliotoxin is a secondary metabolite, the most abundant mycotoxin secreted by A. fumigatus, inhibits the phagocytosis of macrophages and the immune functions of other immune cells . Gliotoxin inhibits inducible NF-κB activity by preventing IκB degradation, which consequently induces host-cell apoptosis. Gliotoxin activates PKA and increases intracellular cAMP concentration; modulates actin cytoskeleton rearrangement to facilitate A. fumigatus internalization into lung epithelial cells.
