Adrenergic Transporter
Adrenergic transporters (NET) are sodium- and chloride-dependent members of the solute carrier family 6 (SLC6) widely distributed throughout the brain within noradrenergic neuronal plasma membranes. They are responsible for re-uptake of adrenalin and noradrenalin.
Products for Adrenergic Transporter
- Cat.No. Product Name Information/Activity
-
BCC5033
Amitriptyline HCl
Amitriptyline hydrochloride is a dibenzocycloheptene-derivative tricyclic antidepressant (TCA).
-
BCC7925
Bicifadine hydrochloride
66504-75-4
-
BCC5901
BTS 54-505 hydrochloride
84484-78-6
-
BCC5943
Cocaine hydrochloride
53-21-4
-
BCC7553
Desipramine hydrochloride
Desipramine hydrochloride is an inhibitor of norepinephrine transporter (NET), 5-HT transporter (SERT) and dopamine transporter (DAT) with Kis of 4, 61 and 78,720 nM, respectively.
-
BCC3773
Duloxetine HCl
Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a serotonin-norepinephrine reuptake inhibitor (SNRI) with a Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD).
-
BCC7123
Indatraline hydrochloride
96850-13-4
-
BCC7402
Lofepramine
Lofepramine (Lopramine) is a potent tricyclic antidepressant and is extensively metabolised to Desipramine. The antidepressant activity of Lofepramine stems from the facilitation of noradrenergic neurotransmission by uptake inhibition. Lofepramine may also potentiate serotoninergic neurotransmission by inhibition of the neuronal uptake of serotonin and the enzyme tryptophan pyrrolase. Lofepramine has significant anxiolytic efficacy in addition to its antidepressant properties.
-
BCC4329
Maprotiline HCl
Maprotiline hydrochloride is a selective noradrenalin re-uptake inhibitor and a tetracyclic antidepressant.
-
BCC7267
(±)-McN 5652
Potent, orally active 5-HT uptake inhibitor. Also inhibits noradrenalin and dopamine uptake <em>in vitro</em>
