Pain and Inflammation Research

Although separate conditions, pain and inflammation are nearly always associated with each other. Pain is defined by the International Association for the Study of Pain (IASP) as 'an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage'. Inflammation is the tissue's immunologic response to injury, characterized by mobilization of white blood cells and antibodies, swelling, and fluid accumulation.

Pain and Inflammation Research Products Areas

Products for Pain and Inflammation Research - Page 57

  1. Cat.No. Product Name Information/Activity
  2. BCC5957 DPNI-caged-GABA Nitroindoline-caged GABA DPNI-caged-GABA chemical structure
  3. BCC6575 Isoguvacine hydrochloride Isoguvacine hydrochloride is a GABA receptor agonist. Isoguvacine hydrochloride chemical structure
  4. BCC7617 L-838,417 286456-42-6 L-838,417 chemical structure
  5. BCC6170 MK 0343 MK0343 (MRK-409) is an orally bioavailable GABAA receptor subtype-selective partial agonist. MK0343 is a non-sedating anxiolytic. MK 0343 chemical structure
  6. BCC6070 MRK 016 783331-24-8 MRK 016 chemical structure
  7. BCC6593 Muscimol Potent GABA<sub>A</sub> agonist Muscimol chemical structure
  8. BCC6564 TACA 38090-53-8 TACA chemical structure
  9. BCC7819 TCS 1205 355022-97-8 TCS 1205 chemical structure
  10. BCC6803 THIP hydrochloride Gaboxadol hydrochloride (Lu 02-030 hydrochloride; THIP hydrochloride) is a potent agonist of the GABAA receptor and an antagonist of GABAC receptors (IC50=25 μM). Gaboxadol hydrochloride displays a partial agonist efficacy on subunit α1β2γ2 with an ED50 value of 143 µM, a full agonist efficacy at α5 subunit (ED50=28-129 µM) and a superagonist efficacy at α4β3δ (ED50=6 µM). Gaboxadol hydrochloride is a non-opioid analgesic and has hypnotic activities. THIP hydrochloride chemical structure
  11. BCC6169 TP 003 628690-75-5 TP 003 chemical structure

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