Arthritis Research
Arthritis is an inflammatory disease of the joints, including the synovium, cartilage, bone, and supporting tissues. It is the leading cause of disability in the US and there are over 100 different types of the disease. The most common types of arthritis are osteoarthritis, rheumatoid arthritis and gout.
Arthritis Research Products Targets
- Matrix Metalloprotease (16)
- Cell Adhesion Molecule (21)
- Leukotriene and Related Receptor (13)
- Others (7)
- Glucocorticoid Receptor (9)
- Focal Adhesion Kinase (4)
- Cyclooxygenases (24)
- Arthritis Research » Complement (2)
- Calcium-Sensitive Protease Modulators (12)
- Chemokine CXC Receptor (9)
- Chemokine CC Receptor (13)
- p38 MAPK (16)
- Janus N-terminal Kinase (12)
- Rho-Kinases (9)
- NO donors and precursors (9)
- nNOS (5)
- iNOS (11)
- eNOS (1)
- Cytokine (15)
Products for Arthritis Research - Page 3
- Cat.No. Product Name Information/Activity
-
BCC1576
FK 3311
FK 3311 (COX-2 Inhibitor V) is a selective inhibitor of COX-2 with antiinflammatory agent.
-
BCC3781
Flurbiprofen
Flurbiprofen is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity.
-
BCC7092
FR 122047 hydrochloride
130717-51-0
-
BCC4042
(S)-(+)-Ibuprofen
(S)-(+)-Ibuprofen is the S(+)-enantiomer of Ibuprofen that inhibits COX-1 and COX-2 activity with IC50s of 2.1 μM and 1.6 μM. (S)-(+)-Ibuprofen has analgesic, antiinflammatory and antipyretic effects.
-
BCC3794
Indomethacin
Indomethacin (Indometacin) is a potent and nonselective inhibitor of COX1 and COX2, with IC50s of 18 nM and 26 nM for human COX-1 and COX-2, respectively, in CHO cells.
-
BCC6490
Naproxen Sodium
Naproxen sodium is a COX-1 and COX-2 inhibitor with IC50s of 8.72 and 5.15 μM, respectively in cell assay.
-
BCC7944
NCX 4040
287118-97-2
-
BCC6219
NCX 466
1262956-64-8
-
BCC6857
NS 398
NS-398 is a non-steroidal an-inflammatory agent with analgesic and antipyretic effects, and selectively inhibits prostaglandin G/H synthase 2/cyclooxygenase 2 (COX-2) activity, with an IC50 of 3.8 μM, and has no effect on COX-1 at 100 μM.
-
BCC3841
Piroxicam
Piroxicam (CP-16171) is a non-steroidal anti-inflammatory drugs, acts as a COX inhibitor, with IC50s of 47, 25 μM for human monocyte COX-1 and COX-2, respectively.


