Lipoxygenase
Lipoxygenases (LOXs) are a family of non-heme iron dioxygenases that are involved in the production and metabolism of fatty acid hydroperoxidases. There are six lipoxygenase isozymes; 5-LOX, 12R-LOX, 12S-LOX, 15-LOX-1, 15-LOX-2 and E-LOX.
Products for Lipoxygenase
- Cat.No. Product Name Information/Activity
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BCN5599
Baicalein
Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase inhibitor with an IC50 value of 3.12 mM.
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BCC6038
BAY-X 1005
Veliflapon (BAY X 1005; DG-031) is an orally active and selective 5-lipoxygenase activating protein (FLAP) inhibitor. Veliflapon inhibits the synthesis of the leukotrienes B4 and C4.
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BCC7013
BW-B 70C
5-Lipoxygenase inhibitor
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BCC7017
MK 886
MK886 is a potent 5-lipoxygenase activating protein inhibitor (FLAP) also a non-competitive inhibitor of PPAR alpha. a potent inhibitor of leukotriene (LT) biosynthesis in intact human polymorphonuclear leukocytes with IC 50 of 2.5 nM. Block the synthessis of leukotrien intact activate leukocyte.
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BCC7504
PD 146176
PD146176 (NSC168807) is a 15-Lipoxygenase (15-LO) inhibitor, which inhibits rabbit reticulocyte 15-LO with a Ki of 197 nM. PD146176 (NSC168807) has a dramatic effect in reducing atherogenesis.
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BCC7288
STEARDA
105955-10-0
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BCC6735
2-TEDC
132465-10-2
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BCC2515
Zileuton
Zileuton is a potent and selective inhibitor of 5-lipoxygenase with antiasthmatic properties.
