Respiratory System Research

The respiratory system consists of the lungs, airways, diaphragm, trachea (windpipe) and pharynx (throat) and its primary function is the exchange of oxygen and carbon dioxide- breathing in and out. Between 6 and 10 liters of air are brought in and out of the lungs and 0.3 liters of oxygen are transferred from the alveoli to the blood per minute.

Respiratory System Research Products Areas

Products for Respiratory System Research - Page 2

  1. Cat.No. Product Name Information/Activity
  2. BCC5269 Acetaminophen Acetaminophen (paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic drug. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor. Acetaminophen chemical structure
  3. BCC2097 Aspirin (Acetylsalicylic acid) Aspirin is a non-selective and irreversible inhibitor of COX-1 and COX-2 with IC50s of 5 and 210 μg/mL. Aspirin (Acetylsalicylic acid) chemical structure
  4. BCC1099 Celecoxib Celecoxib is a selective COX-2 inhibitor with an IC50 of 40 nM. Celecoxib chemical structure
  5. BCC4439 Diclofenac Sodium Diclofenac Sodium (GP 45840) is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively. Diclofenac Sodium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade. Diclofenac Sodium chemical structure
  6. BCC7064 DuP 697 DuP-697 is a member of the vicinal diaryl heterocycles and a potent, irreversible, selective and orally active COX-2 inhibitor (IC50 of 10 nM and 800 nM for human COX-2 and COX-1, respectively). DuP-697 exerts antiproliferative (IC50 of 42.8 nM), antiangiogenic and apoptotic effects on HT29 colorectal cancer cells. DuP-697 inhibits prostaglandin synthesis and has anti-inflammatory, anticancer and antipyretic effects. DuP 697 chemical structure
  7. BCC4428 Etodolac Etodolac (AY-24236) is a non-steroidal anti-inflammatory compound that is a non-selective inhibitor of COX (IC50=53.5 nM) Etodolac chemical structure
  8. BCC1576 FK 3311 FK 3311 (COX-2 Inhibitor V) is a selective inhibitor of COX-2 with antiinflammatory agent. FK 3311 chemical structure
  9. BCC3781 Flurbiprofen Flurbiprofen is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity. Flurbiprofen chemical structure
  10. BCC7092 FR 122047 hydrochloride 130717-51-0 FR 122047 hydrochloride chemical structure
  11. BCC4042 (S)-(+)-Ibuprofen (S)-(+)-Ibuprofen is the S(+)-enantiomer of Ibuprofen that inhibits COX-1 and COX-2 activity with IC50s of 2.1 μM and 1.6 μM. (S)-(+)-Ibuprofen has analgesic, antiinflammatory and antipyretic effects. (S)-(+)-Ibuprofen chemical structure

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