Melanocortin (MC) Receptors - GPCR/G protein

Cat.No. Product Name Information

BCC7414 Melanotan II Melanotan (MT)-II, a synthetic melanocortin receptor agonist, is an injectable peptide hormone used to promote tanning.

BCC6028 ACTH (1-39) Adrenocorticotropic Hormone (ACTH) (1-39), human is a melanocortin receptor agonist.

BCC6049 Lys-γ3-MSH

BCC6019 SHU 9119 SHU 9119 is a potent human melanocortin 3 and 4 receptors (MC3/4R) antagonist and a partial MC5R agonist; with IC50 values of 0.23, 0.06, and 0.09 nM for human MC3R, MC4R and MC5R, respectively.

BCC5819 HS 014 HS 014

BCC5820 HS 024 HS 024

BCC7539 THIQ THIQ is the first selective agonist of the melanocortin-4 receptor (MC4R), with high affinity and potency for hMC4R (IC50=1.2 nM, EC50=2.1 nM) and rMC4R (IC50=0.6 nM, EC50=2.9 nM). THIQ maintains low potency at MC1R, MC3R and MC5R. THIQ plays a role in eliciting erectile activity in rodents. THIQ acts as a pharmacoperone of the MC4R rescuing the cell surface expression and signaling of some intracellularly retained MC4R mutants. THIQ

BCC7902 [D-Trp8]-γ-MSH

BCC6022 JKC 363 JKC 363

BCC7850 BMS 470539 dihydrochloride Potent, selective MC<sub>1</sub> receptor agonist

BCC6025 MCL 0020

BCC7420 α-MSH α-Melanocyte-Stimulating Hormone (MSH), amide stimulates melanocortin 1 receptor that results in the activation of adenylyl cyclase. α-MSH

BCC6363 PG 931 PG 931

BCC6021 γ1-MSH γ1-MSH

BCC5963 [Nle4,D-Phe7]-α-MSH Melanotan I is a synthetic analogue of α-melanocyte stimulating hormone (α-MSH), for gaining a tan.

BCC6330 PG 106 PG 106

Products for Melanocortin (MC) Receptors