Products for TLR
- Cat.No. Product Name Information
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BCC6245
Pam3CSK4
Pam3CSK4 is a toll-like receptor 1/2 (TLR1/2) agonist with an EC50 of 0.47 ng/mL for human TLR1/2.
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BCC7460
RWJ 21757
Loxoribine (7-Allyl-8-oxoguanosine) is a guanosine analog with anti-viral and anti-tumor activities. Loxoribine is an orally bioavailable and selective Toll-like receptor (TLR) 7 agonist.
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BCC6319
CU CPT 4a
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BCC6320
CU CPT 22
CU-CPT22 is a potent protein complex of toll-like receptor 1 and 2 (TLR1/2) inhibitor, and competes with the synthetic triacylated lipoprotein (Pam3CSK4) binding to TLR1/2 with a Ki of 0.41 µM. CU-CPT22 blocks Pam3CSK4-induced TLR1/2 activation with an IC50 of 0.58 µM.
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BCC1977
TAK-242
Resatorvid (TAK-242) is a selective Toll-like receptor 4 (TLR4) inhibitor. Resatorvid inhibits NO, TNF-R and IL-6 production with IC50s of 1.8 nM, 1.9 nM and 1.3 nM, respectively. Resatorvid downregulates expression of TLR4 downstream signaling molecules MyD88 and TRIF. Resatorvid inhibits autophagy and plays pivotal role in various inflammatory diseases.
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BCC6138
Poly(I:C)
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BCC6247
Pam2CSK4
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BCC4197
Imiquimod maleate
Imiquimod maleate is an immune response modifier that acts as a toll-like receptor 7agonist.
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BCC4196
Imiquimod hydrochloride
Imiquimod hydrochloride is an immune response modifier that acts as a toll-like receptor 7agonist.
