Dopamine Receptor - Neuroscience

Cat.No. Product Name Information

BCC5381 GBR 12935 GBR 12935 is a potent, and selective dopamine reuptake inhibitor.

BCC6886 L-741,626 L-741626 is a selective D2 dopamine receptor antagonist, with the Ki values of 2.4, 100 and 220 nM for human D2, D3 and D4 receptors respectively.

BCC4252 Amisulpride hydrochloride Amisulpride hydrochloride is a dopamine D2/D3 receptor antagonist with Kis of 2.8 and 3.2 nM for human dopamine D2 and D3, respectively.

BCC5276 Cabergoline Cabergoline is an ergot derived-dopamine D2-like receptor agonist that has high affinity for D2, D3, and 5-HT2B receptors (Ki=0.7, 1.5, and 1.2, respectively).

BCC1453 Cariprazine Cariprazine is a novel antipsychotic drug candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM).

BCC7184 Raclopride Raclopride is a dopamine D2/D3 receptor antagonist, which binds to D2 and D3 receptors with dissociation constants (Kis) of 1.8 nM and 3.5 nM, respectively, but has a very low affinity for D1 and D4 receptors with Kis of 18000 nM and 2400 nM, respectively.

BCC6747 (+)-AJ 76 hydrochloride Antagonist; preferential action at D<sub>2</sub>-like autoreceptors

BCC6917 (-)-Quinpirole hydrochloride Quinpirole Hydrochloride ((-)-LY 171555) is a high-affinity agonist of dopamine D2/D3 receptor.

BCC5695 L-745,870 trihydrochloride

BCC5696 L-741,742 hydrochloride

BCC4118 Brexpiprazole Brexpiprazole (OPC-34712), an atypical antipsychotic drug, is a partial agonist of human 5-HT1A and dopamine receptor with Kis of 0.12 nM and 0.3 nM, respectively. Brexpiprazole is also a 5-HT2A receptor antagonist with a Ki of 0.47 nM.

BCC7100 Quinelorane hydrochloride

BCC7193 Eticlopride hydrochloride

Products for Dopamine Receptor