Amisulpride hydrochlorideDopamine D2/D3 receptor antagonist CAS# 81342-13-4 |
Related Products
- Nateglinide
Catalog No.:BCC5005
CAS No.:105816-04-4
- Dronedarone
Catalog No.:BCN2176
CAS No.:141626-36-0
- Gliclazide
Catalog No.:BCC5002
CAS No.:21187-98-4
- Tolbutamide
Catalog No.:BCC5001
CAS No.:64-77-7
- Nicorandil
Catalog No.:BCC5004
CAS No.:65141-46-0
Quality Control & MSDS
3D structure
Package In Stock
Number of papers citing our products
| Cas No. | 81342-13-4 | SDF | Download SDF |
| PubChem ID | 10046897 | Appearance | Powder |
| Formula | C17H28ClN3O4S | M.Wt | 405.94 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 4-amino-N-[(1-ethylpyrrolidin-2-yl)methyl]-5-ethylsulfonyl-2-methoxybenzamide;hydrochloride | ||
| SMILES | CCN1CCCC1CNC(=O)C2=CC(=C(C=C2OC)N)S(=O)(=O)CC.Cl | ||
| Standard InChIKey | XFOYXFDTUMXXFP-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C17H27N3O4S.ClH/c1-4-20-8-6-7-12(20)11-19-17(21)13-9-16(25(22,23)5-2)14(18)10-15(13)24-3;/h9-10,12H,4-8,11,18H2,1-3H3,(H,19,21);1H | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
Amisulpride hydrochloride Dilution Calculator
Amisulpride hydrochloride Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.4634 mL | 12.3171 mL | 24.6342 mL | 49.2684 mL | 61.5855 mL |
| 5 mM | 0.4927 mL | 2.4634 mL | 4.9268 mL | 9.8537 mL | 12.3171 mL |
| 10 mM | 0.2463 mL | 1.2317 mL | 2.4634 mL | 4.9268 mL | 6.1585 mL |
| 50 mM | 0.0493 mL | 0.2463 mL | 0.4927 mL | 0.9854 mL | 1.2317 mL |
| 100 mM | 0.0246 mL | 0.1232 mL | 0.2463 mL | 0.4927 mL | 0.6159 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
Amisulpride hydrochloride is an atypical antagonist of dopamine D2/D3 receptor with Ki values of 2.8±0.4nM and 3.2±0.3nM for D2 and D3 receptor subtypes, respectively [1].
Amisulpride hydrochloride has shown high affinity to the cloned and stably transfected human dopamine D2 with Ki values of 2.8±0.4nM and 3.2±0.3nM for D2 and D3 receptor subtypes, respectively. Amisulpride hydrochloride has been reported to inhibit radioligand binding to native dopamine D2 receptor in membranes from the rat striatum with an IC50 value of 21nM. Besides, Amisulpride hydrochloride has been revealed to displace [3H]raclopride binding in vivo with an ED50 value of 17.3±1.86mg/kg in the rat limbic system. In addition, Amisulpride hydrochloride has been noted to inhibit quinpirole-induced [3H]thymidine with an IC50 value of 22±3nM [1].
References:
[1] Schoemaker H1, Claustre Y, Fage D, Rouquier L, Chergui K, Curet O, Oblin A, Gonon F, Carter C, Benavides J, Scatton B.Neurochemical characteristics of amisulpride, an atypical dopamine D2/D3 receptor antagonist with both presynaptic and limbic selectivity. J Pharmacol Exp Ther. 1997 Jan;280(1):83-97.
Featured Products
- D-AP7
Catalog No.:BCC6559
CAS No.:81338-23-0
- ent-6,9-Dihydroxy-15-oxo-16-kauren-19-oic acid
Catalog No.:BCN1342
CAS No.:81264-00-8
- ent-6,9-Dihydroxy-15-oxo-16-kauren-19-oic acid beta-D-glucopyranosyl ester
Catalog No.:BCN1343
CAS No.:81263-98-1
- ent-6,11-Dihydroxy-15-oxo-16-kauren-19-oic acid beta-D-glucopyranosyl ester
Catalog No.:BCN1344
CAS No.:81263-97-0
- ent-9-Hydroxy-15-oxo-16-kauren-19-oic acid beta-D-glucopyranosyl ester
Catalog No.:BCN1345
CAS No.:81263-96-9
- 15-Deoxoeucosterol
Catalog No.:BCN4348
CAS No.:81241-53-4
- L-741,626
Catalog No.:BCC6886
CAS No.:81226-60-0
- Panaxynol
Catalog No.:BCN3833
CAS No.:81203-57-8
- Boc-D-Tyr(2-Br-Z)-OH
Catalog No.:BCC3464
CAS No.:81189-61-9
- Apatinib
Catalog No.:BCC5099
CAS No.:811803-05-1
- Imiloxan hydrochloride
Catalog No.:BCC6875
CAS No.:81167-22-8
- RR-src
Catalog No.:BCC6956
CAS No.:81156-93-6
New Products
- Schisandrin C epoxide
Catalog No.:BCN3744
CAS No.:81345-36-0
- Cyclo(Tyr-Hpro)
Catalog No.:BCN2424
CAS No.:813461-21-1
- Momordicoside F1
Catalog No.:BCN3273
CAS No.:81348-81-4
- Momordicoside L
Catalog No.:BCN3274
CAS No.:81348-83-6
- Momordicoside K
Catalog No.:BCN3272
CAS No.:81348-84-7
- Momordicoside G
Catalog No.:BCN4349
CAS No.:81371-54-2
- Seglitide
Catalog No.:BCC7191
CAS No.:81377-02-8
- Fmoc-His(Boc)-OH.CHA
Catalog No.:BCC2595
CAS No.:81379-52-4
- Acetylvalerenolic acid
Catalog No.:BCC8112
CAS No.:81397-67-3
- Alfuzosin HCl
Catalog No.:BCC2494
CAS No.:81403-68-1
- Alfuzosin
Catalog No.:BCC4080
CAS No.:81403-80-7
- EHNA hydrochloride
Catalog No.:BCC6996
CAS No.:81408-49-3
Amisulpride hydrochloride is a dopamine D2/D3 receptor antagonist with Kis of 2.8 and 3.2 nM for human dopamine D2 and D3, respectively.
Amisulpride hydrochloride,81342-13-4,Natural Products,Dopamine Receptor, buy Amisulpride hydrochloride , Amisulpride hydrochloride supplier , purchase Amisulpride hydrochloride , Amisulpride hydrochloride cost , Amisulpride hydrochloride manufacturer , order Amisulpride hydrochloride , high purity Amisulpride hydrochloride
